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将营养干预的益处扩展至手术环境之外。

Extending the benefit of nutrition intervention beyond the operative setting.

作者信息

Nogueira Paulo L Batista, Dock-Nascimento Diana B, de Aguilar-Nascimento José E

机构信息

UNIVAG Medical School, Varzea Grande.

Health Sciences Postgraduate Department, Medical School, Federal University of Mato Grosso, Cuiabá, Brazil.

出版信息

Curr Opin Clin Nutr Metab Care. 2022 Nov 1;25(6):388-392. doi: 10.1097/MCO.0000000000000868. Epub 2022 Aug 24.

Abstract

PURPOSE OF REVIEW

To provide an update of the recent evidence on the potential of perioperative nutritional interventions to benefit adult patients undergoing head and neck and digestive procedures.

RECENT FINDINGS

Perioperative nutrition within multimodal prehabilitation programs improve postoperative outcomes. Perioperative fasting time can be reduced with beverages containing carbohydrate alone or blended with a nitrogenous source such as whey protein; this approach seems to be safe and improve outcome. The choice of protein-containing formula, as well as diet composition to be recommended early during the postoperative refeeding, can be optimized to reduce complications. Sarcopenia is an important risk factor for surgical patients, as such, prehabilitation along with preoperative nutrition is strongly advised. Perioperative supplementation with β-hydroxy β-methylbutyrate to mitigate sarcopenia requires further investigation. Although perioperative nutritional interventions reduce healthcare costs, recent data suggest it has been scarcely prescribed.

SUMMARY

Nutritional intervention is key in multimodal programs of enhanced recovery after surgery to ensure better outcomes. Perioperative fasting should be shortened, and include clear fluids containing carbohydrates and protein, especially in the early postoperative period. Multimodal prehabilitation is key to mitigate sarcopenia. Action to improve knowledge on the cost-effectiveness of nutritional interventions in the perioperative setting are needed.

摘要

综述目的

提供近期证据的更新,以探讨围手术期营养干预对接受头颈及消化系统手术的成年患者的潜在益处。

最新发现

多模式术前康复计划中的围手术期营养可改善术后结局。单独含碳水化合物或与含氮源(如乳清蛋白)混合的饮料可缩短围手术期禁食时间;这种方法似乎是安全的且能改善结局。术后早期重新进食时,含蛋白质配方的选择以及推荐的饮食组成可进行优化以减少并发症。肌肉减少症是手术患者的重要危险因素,因此,强烈建议进行术前康复以及术前营养支持。围手术期补充β-羟基-β-甲基丁酸以减轻肌肉减少症需要进一步研究。尽管围手术期营养干预可降低医疗成本,但近期数据表明其应用极少。

总结

营养干预是多模式术后加速康复计划的关键,以确保更好的结局。应缩短围手术期禁食时间,包括含碳水化合物和蛋白质的清液,尤其是在术后早期。多模式术前康复是减轻肌肉减少症的关键。需要采取行动提高对围手术期营养干预成本效益的认识。

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