Brancaccio Marco
UK Dementia Research Institute at Imperial College London, Department of Brain Sciences, Imperial College London, London, UK.
Neuron. 2022 Oct 5;110(19):3058-3060. doi: 10.1016/j.neuron.2022.08.024.
Glia-neuronal interplay is critical for circadian regulation of physiology and behavior. In this issue of Neuron, Vaughen et al. identify daily variations of glycosphingolipids that depend on glia and whose disruption alters proteostasis and daily structural plasticity of Drosophila circadian circuits.
神经胶质细胞与神经元之间的相互作用对于生理和行为的昼夜节律调节至关重要。在本期《神经元》杂志中,沃恩等人发现了神经节苷脂的每日变化,这些变化依赖于神经胶质细胞,其破坏会改变果蝇昼夜节律回路的蛋白质稳态和每日结构可塑性。