Kisamo Ombeni, Kilonzi Manase, Mikomangwa Wigilya P, Bwire George M, Mlyuka Hamu J, Marealle Alphonce I, Mutagonda Ritah F
Department of Clinical Pharmacy and Pharmacology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Department of Pharmaceutical Microbiology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Med Access Point Care. 2020 Jan 27;4:2399202619900148. doi: 10.1177/2399202619900148. eCollection 2020 Jan-Dec.
Tanzania National Treatment Guidelines and National Therapeutic Committee circular of 2012 requires prescribers to prescribe medicines using their generic names as recommended by the World Health Organization. The implementation of the aforementioned recommendations by prescribers is not well documented in our settings. Therefore, this study aimed to explore the compliance on the use of generic names by prescribers at Muhimbili National Hospital.
A descriptive cross-sectional study was conducted at Muhimbili National Hospital from January to May 2019 in both inpatient and outpatient pharmacy units. Data were analyzed using SPSS, version 23. Chi-square test was used to analyze proportions between the different variables of the study. A -value for significance was <0.05.
Of 1001 prescriptions analyzed, 71.6% contained medicines prescribed using brand names. The mean (±standard deviation (SD)) number of medicines per prescription was 2.98 (±1.5). The most frequently prescribed medicines by brand names were a combination of vitamin and mineral supplements (34.4%) followed by antibiotics (26.7%). Medical doctors (25.6%) and medical specialists (21.6%) prescribed ⩾2 medicines using brand names per prescription compared to interns (15.0%) and residents (6.9%) ( < 0.001).
Prescribing medicines using brand names was highly observed in this study. Supplements and antibiotics were among the products that were highly prescribed using their brand names. Qualitative studies to explore reasons for brand name prescribing practices are recommended.
坦桑尼亚国家治疗指南和2012年国家治疗委员会通知要求开处方者按照世界卫生组织的建议使用药品通用名开处方。在我们的环境中，开处方者对上述建议的执行情况记录不佳。因此，本研究旨在探讨穆希姆比利国家医院开处方者使用通用名的依从性。
2019年1月至5月在穆希姆比利国家医院的住院和门诊药房进行了一项描述性横断面研究。使用SPSS 23版软件进行数据分析。卡方检验用于分析研究中不同变量之间的比例。显著性的P值<0.05。
在分析的1001张处方中，71.6%包含使用商品名开具的药品。每张处方的药品平均数量（±标准差）为2.98（±1.5）。最常使用商品名开具的药品是维生素和矿物质补充剂组合（34.4%），其次是抗生素（26.7%）。与实习医生（15.0%）和住院医生（6.9%）相比，医生（25.6%）和医学专家（21.6%）每张处方使用商品名开具的药品≥2种（P<0.001）。
本研究中使用商品名开处方的情况很常见。补充剂和抗生素是使用商品名开具频率较高的产品。建议进行定性研究以探讨使用商品名开处方做法的原因。
