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环境中促进和限制抗菌药物耐药性的因素——现有知识空白

Factors promoting and limiting antimicrobial resistance in the environment - Existing knowledge gaps.

作者信息

Goryluk-Salmonowicz Agata, Popowska Magdalena

机构信息

Department of Bacterial Physiology, Institute of Microbiology, Faculty of Biology, University of Warsaw, Warsaw, Poland.

出版信息

Front Microbiol. 2022 Sep 20;13:992268. doi: 10.3389/fmicb.2022.992268. eCollection 2022.

Abstract

The dissemination of multidrug-resistant bacteria strains and genes carrying antibiotic resistance is currently considered to be one of the most important global problem. The WHO calls for the need to contain the spread of Antimicrobial Resistance (AMR) from all possible sources. There have been many international actions grouping scientists studying this phenomenon, and quite a lot of scientific projects devoted to this problem have already been carried out. As well, so far several strategies have been developed that can inhibit the AMR spread. In this mini-review, we highlight overlooked aspects that seem to be crucial for creating a comprehensive picture of AMR, especially in the context of One Health approach.

摘要

多重耐药细菌菌株以及携带抗生素抗性的基因的传播目前被认为是全球最重要的问题之一。世界卫生组织呼吁有必要遏制来自所有可能来源的抗菌药物耐药性(AMR)的传播。已经有许多国际行动将研究这一现象的科学家聚集在一起,并且已经开展了相当多致力于这个问题的科学项目。同样,到目前为止已经制定了几种可以抑制AMR传播的策略。在这篇小型综述中,我们强调了一些被忽视的方面,这些方面似乎对于全面了解AMR至关重要,特别是在“同一健康”方法的背景下。

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