2022 年 5 月至 7 月，在英格兰的教育环境中接触确诊病例后，工作人员和学生感染猴痘的风险极低。
Very low risk of monkeypox among staff and students after exposure to a confirmed case in educational settings, England, May to July 2022.
机构信息
Immunisation Division, UK Health Security Agency, London, United Kingdom.
Paediatric Infectious Diseases Research Group, St. George's University of London, London, United Kingdom.
出版信息
Euro Surveill. 2022 Oct;27(40). doi: 10.2807/1560-7917.ES.2022.27.40.2200734.
Abstract
We investigated a secondary school (11-16 year-olds), a primary school (5-11 year-olds), reception year (4-5 year-olds) and a nursery (2-5 year-olds) following confirmed monkeypox in an adult in each educational setting during June and July 2022. MVA-BN vaccine was offered up to 14 days post exposure to 186 children < 12 years and 21 were vaccinated. No secondary cases occurred among at least 340 exposed students and more than 100 exposed staff during the 28-day follow-up period.
摘要
我们调查了一所中学（11-16 岁）、一所小学（5-11 岁）、一个幼儿园（4-5 岁）和一个托儿所（2-5 岁），这些机构都在 2022 年 6 月至 7 月期间在成年感染者中发现了猴痘确诊病例。MVA-BN 疫苗在暴露后 14 天内提供给 186 名<12 岁的儿童，其中 21 人接种了疫苗。在至少 340 名暴露学生和 100 多名暴露教职员工的 28 天随访期间，没有发生二次感染病例。
相似文献
1
Very low risk of monkeypox among staff and students after exposure to a confirmed case in educational settings, England, May to July 2022.2022 年 5 月至 7 月，在英格兰的教育环境中接触确诊病例后，工作人员和学生感染猴痘的风险极低。
Euro Surveill. 2022 Oct;27(40). doi: 10.2807/1560-7917.ES.2022.27.40.2200734.
2
SARS-CoV-2 infection and transmission in educational settings: a prospective, cross-sectional analysis of infection clusters and outbreaks in England.SARS-CoV-2 感染与传播在教育环境中的情况：对英格兰感染集群和疫情的前瞻性、横断面分析。
Lancet Infect Dis. 2021 Mar;21(3):344-353. doi: 10.1016/S1473-3099(20)30882-3. Epub 2020 Dec 8.
3
SARS-CoV-2 infection and transmission in primary schools in England in June-December, 2020 (sKIDs): an active, prospective surveillance study.2020 年 6 月至 12 月英国小学中的 SARS-CoV-2 感染和传播（sKIDs）：一项主动、前瞻性监测研究。
Lancet Child Adolesc Health. 2021 Jun;5(6):417-427. doi: 10.1016/S2352-4642(21)00061-4. Epub 2021 Mar 17.
4
One dose of varicella vaccine does not prevent school outbreaks: is it time for a second dose?一剂水痘疫苗无法预防学校爆发疫情：是时候接种第二剂了吗？
Pediatrics. 2006 Jun;117(6):e1070-7. doi: 10.1542/peds.2005-2085.
5
COVID-19 outbreaks following full reopening of primary and secondary schools in England: Cross-sectional national surveillance, November 2020.2020年11月英国中小学全面复课后的新冠疫情：全国横断面监测
Lancet Reg Health Eur. 2021 Jul;6:100120. doi: 10.1016/j.lanepe.2021.100120. Epub 2021 May 19.
6
Secondary attack rates in primary and secondary school bubbles following a confirmed case: Active, prospective national surveillance, November to December 2020, England.2020 年 11 月至 12 月，英国在确诊病例后对中小学“泡泡”开展的主动、前瞻性全国监测：次要发病数。
PLoS One. 2022 Feb 16;17(2):e0262515. doi: 10.1371/journal.pone.0262515. eCollection 2022.
7
Low levels of monkeypox virus-neutralizing antibodies after MVA-BN vaccination in healthy individuals.健康个体中 MVA-BN 疫苗接种后，猴痘病毒中和抗体水平较低。
Nat Med. 2023 Jan;29(1):270-278. doi: 10.1038/s41591-022-02090-w. Epub 2022 Oct 18.
8
An outbreak of hepatitis A virus infection in a secondary school in England with no undetected asymptomatic transmission among students.英国一所中学发生甲型肝炎病毒感染暴发，学生中无未检出的无症状传播。
Epidemiol Infect. 2022 Dec 11;151:e6. doi: 10.1017/S095026882200190X.
9
The COVID-19 Schools Infection Survey in England: Protocol and Participation Profile for a Prospective Observational Cohort Study.英格兰的新冠疫情学校感染调查：一项前瞻性观察队列研究的方案与参与情况简介
JMIR Res Protoc. 2022 Nov 10;11(11):e34075. doi: 10.2196/34075.
10
The Monkeypox Outbreak 2022: Women and Children Patients.2022 年猴痘疫情：女性和儿童患者。
Skinmed. 2022 Oct 31;20(5):334-335. eCollection 2022.
引用本文的文献
1
Mpox in children and adolescents and contact follow-up in school settings in greater Paris, France, May 2022 to July 2023.2022 年 5 月至 2023 年 7 月法国大巴黎地区儿童和青少年中的猴痘以及学校环境中的接触者随访。
Euro Surveill. 2024 May;29(21). doi: 10.2807/1560-7917.ES.2024.29.21.2300555.
2
Paediatric, maternal, and congenital mpox: a systematic review and meta-analysis.儿科、孕产妇和先天性猴痘：系统评价和荟萃分析。
Lancet Glob Health. 2024 Apr;12(4):e572-e588. doi: 10.1016/S2214-109X(23)00607-1. Epub 2024 Feb 21.
3
Willingness to accept monkeypox vaccine and its correlates among men who have sex with men in Southern China: a web-based online cross-sectional study.中国南方男男性行为者对接种猴痘疫苗的意愿及其相关因素：一项基于网络的横断面研究。
Front Public Health. 2024 Feb 7;12:1289918. doi: 10.3389/fpubh.2024.1289918. eCollection 2024.
4
Analysis of tweets discussing the risk of Mpox among children and young people in school (May-October 2022): a retrospective observational study.分析 2022 年 5 月至 10 月期间在学校中讨论猴痘病毒在儿童和青少年中风险的推文：一项回顾性观察研究。
BMJ Paediatr Open. 2024 Jan 31;8(1):e002236. doi: 10.1136/bmjpo-2023-002236.
5
The role of vaccination and public awareness in forecasts of Mpox incidence in the United Kingdom.疫苗接种和公众意识在预测英国猴痘发病率中的作用。
Nat Commun. 2023 Jul 11;14(1):4100. doi: 10.1038/s41467-023-38816-8.
6
School-based interventions on Mpox: A scoping review.基于学校的猴痘干预措施：一项范围综述。
Health Sci Rep. 2023 Jun 12;6(6):e1334. doi: 10.1002/hsr2.1334. eCollection 2023 Jun.
7
A European perspective of phylogenomics, sublineages, geographical distribution, epidemiology, and mutational landscape of mpox virus: Emergence pattern may help to fight the next public health emergency in Europe.一个关于猴痘病毒的系统发生基因组学、亚谱系、地理分布、流行病学和突变景观的欧洲视角：出现模式可能有助于应对欧洲下一次公共卫生紧急事件。
J Infect Public Health. 2023 Jul;16(7):1004-1014. doi: 10.1016/j.jiph.2023.04.017. Epub 2023 Apr 29.
8
Monkeypox Cross-Sectional Survey of Knowledge, Attitudes, Practices, and Willingness to Vaccinate among University Students in Pakistan.巴基斯坦大学生中猴痘知识、态度、行为及接种意愿的横断面调查
Vaccines (Basel). 2022 Dec 31;11(1):97. doi: 10.3390/vaccines11010097.
本文引用的文献
1
Monkeypox and children.猴痘与儿童
Arch Dis Child. 2022 Dec;107(12):1065-1066. doi: 10.1136/archdischild-2022-324703. Epub 2022 Sep 2.
2
Comment Title: Care of children exposed to monkeypox.评论标题：接触猴痘儿童的护理
Lancet Reg Health Eur. 2022 Sep 7;21:100514. doi: 10.1016/j.lanepe.2022.100514. eCollection 2022 Oct.
3
Monkeypox virus infections in children in Spain during the first months of the 2022 outbreak.2022年疫情爆发头几个月西班牙儿童的猴痘病毒感染情况。
Lancet Child Adolesc Health. 2022 Nov;6(11):e22-e23. doi: 10.1016/S2352-4642(22)00250-4. Epub 2022 Sep 2.
4
The monkeypox outbreak: risks to children and pregnant women.猴痘疫情：对儿童和孕妇的风险。
Lancet Child Adolesc Health. 2022 Nov;6(11):751-753. doi: 10.1016/S2352-4642(22)00223-1. Epub 2022 Aug 1.
5
Paediatric monkeypox patient with unknown source of infection, the Netherlands, June 2022.荷兰 2022 年 6 月，一名来源不明的小儿猴痘感染病例。
Euro Surveill. 2022 Jul;27(29). doi: 10.2807/1560-7917.ES.2022.27.29.2200552.
Zotero 插件