Grimby G, Einarsson G
Birth Defects Orig Artic Ser. 1987;23(4):265-74.
The main histopathologic finding is large grouping of type I and type II fibers. Subjects with low muscle strength had a large number of type I fibers. Large fibers were found especially in men with low muscle strength. The oxidative enzymatic activity was reduced. The findings suggest a compensatory process, with an increased number of type I fibers in subjects, a large reduction in muscle strength, and also an increase in the fiber size. There is a sex difference in the fiber hypertrophy.
主要组织病理学发现是I型和II型纤维大量聚集。肌肉力量低的受试者有大量I型纤维。大纤维尤其在肌肉力量低的男性中发现。氧化酶活性降低。这些发现提示了一个代偿过程,即受试者中I型纤维数量增加、肌肉力量大幅降低以及纤维大小增加。纤维肥大存在性别差异。