[Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis].
作者信息
Zapadniuk V I, Panteleĭmonova T N
出版信息
Biull Eksp Biol Med. 1987 Jul;104(7):30-2.
PMID:3620644
Abstract
Trimethylglycine at a dose of 1.5 g/kg was found to produce marked bile secretory effect in young and old rats. In rabbits with experimental atherosclerosis, trimethylglycine increased the content of biliary acids in the bile and normalized the indexes of lipid metabolism in the blood serum. Apparently, the effect on cholesterol transformation into biliary acids and its excretion with the bile is one of the mechanisms of anti-atherosclerotic action of trimethylglycine.
摘要
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