Nishanov Kh T, Tumanov V P, Kaem R I, Titova G P
Biull Eksp Biol Med. 1987 Jul;104(7):32-5.
The work was aimed at the elucidation of mechanisms of pathogenetic prevention of acute experimental pancreatitis induced according to the method of Arai. Pathological and biochemical examinations have shown that the application of PNA synthesis inhibitor 5-FU and cellular and intracellular membrane stabilizer-intralipid, infused at the beginning of the experiment, prevented the development of acute purulent pancreatitis.
该研究旨在阐明根据新井法诱导的急性实验性胰腺炎的发病机制预防机制。病理和生化检查表明,在实验开始时注入PNA合成抑制剂5-氟尿嘧啶和细胞及细胞内膜稳定剂——脂肪乳剂,可预防急性化脓性胰腺炎的发展。