Bankova V V, Simutenko L V, Barsegian G G
Biull Eksp Biol Med. 1987 Jul;104(7):40-3.
The rate of lipid peroxidation (LPO) in erythrocytes and brain homogenate has been assessed by the accumulation of malondialdehyde, the degree of erythrocyte autohemolysis, the content of hydrogen peroxide and catalase activity observed in newborn rats aged 1 hour, 1, 15, 20 and 30 days. Pregnant rats were exposed to emotional stress (aggressive interaction of two pregnant rats in an unavoidable conflict situation provoked by nociceptive irritation. Significant age-dependent differences in the rate of LPO (both in erythrocytes and cerebral tissue) have been found. The highest rate was noted in rats 15 days of age. The emotional stress of pregnant females resulted in the changes of behavioural reactions of newborn rats and LPO activity that was characterized by the increase in LPO rate in 1-hour- and 1-day-old rats and by slowing of LPO rate in 15-day-old rats. These phenomena were observed in erythrocytes and brain tissues of test animals.
通过测定丙二醛的积累、红细胞自溶程度、过氧化氢含量以及过氧化氢酶活性，评估了出生1小时、1天、15天、20天和30天的新生大鼠红细胞和脑匀浆中的脂质过氧化（LPO）速率。将怀孕大鼠置于情绪应激状态（在由伤害性刺激引发的不可避免的冲突情境中，两只怀孕大鼠进行攻击性互动）。发现LPO速率（在红细胞和脑组织中）存在显著的年龄依赖性差异。15日龄大鼠的LPO速率最高。怀孕雌性大鼠的情绪应激导致新生大鼠行为反应和LPO活性发生变化，其特征为1小时龄和1日龄大鼠的LPO速率增加，15日龄大鼠的LPO速率减缓。在实验动物的红细胞和脑组织中观察到了这些现象。
