Timoshin S S, Pan'kova T D, Titov M I
Biull Eksp Biol Med. 1987 Aug;104(8):229-30.
The effects of the application of synthetic leu-enkephalin analogue--dalargin and naloxone on DNA synthesis and cell division in corneal epithelium were studied with the drugs injected once or five times. The influence of one and five intraperitoneal injections of the drugs in question at a dose of 10 micrograms/kg body weight was also investigated. In both cases the opioid receptor ligands examined activated DNA synthesis with the following adequate increase in mitotic index.
研究了合成亮脑啡肽类似物——达乐argin和纳洛酮单次或五次注射对角膜上皮细胞DNA合成和细胞分裂的影响。还研究了以10微克/千克体重的剂量腹腔注射一次和五次上述药物的影响。在这两种情况下，所检测的阿片受体配体均激活了DNA合成，并相应地增加了有丝分裂指数。
