Centre for Vestibular and Behavioural Neurosciences, Department of Clinical and Movement Neurosciences, Institute of Neurology, University College London, Queen Square, London, UK; The Ear Institute, University College London, London, UK.
Department of Neuro-otology, Royal national ENT and Eastman Dental Hospitals, University College London Hospitals, London, UK.
J Neurol Sci. 2022 Nov 15;442:120417. doi: 10.1016/j.jns.2022.120417. Epub 2022 Sep 17.
The video head impulse test (vHIT) assesses the vestibulo-ocular reflex (VOR) during a rapid high-velocity low amplitude (10°-20°) head rotation. Patients with peripheral vestibulopathy have a reduced VOR gain with corrective catch-up saccades during the head turn. There are several pitfalls, mainly technical, which may interfere with interpretation of vHIT data. In addition, intrusive eye movement disorders such as spontaneous nystagmus that affect normal eye position and tracking can affect the vHIT results. To date there has been little study of neurological saccadic eye movements that may interfere with the interpretation of vHIT data. Here, in ten patients with a range of central neurological disorders, we describe oculomotor abnormalities on vHIT in the presence of normal range VOR gain values, recorded at a tertiary vestibular neurology service.
视频头脉冲试验（vHIT）评估了快速高速度低幅度（10°-20°）头部旋转过程中的前庭眼反射（VOR）。在头部转动期间，外周前庭病变患者的 VOR 增益降低，并伴有矫正性急跳扫视。存在多种可能干扰 vHIT 数据解释的主要是技术方面的陷阱。此外，侵入性眼球运动障碍，如影响正常眼球位置和跟踪的自发性眼球震颤，可能会影响 vHIT 结果。迄今为止，对于可能干扰 vHIT 数据解释的神经扫视眼运动的研究甚少。在这里，在 10 名患有一系列中枢神经系统疾病的患者中，我们描述了在三级前庭神经病学服务中记录的正常范围 VOR 增益值下，vHIT 存在的眼球运动异常。
