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结肠息肉:血吸虫病的罕见临床表现(病例报告)。

Colonic polyps: a rare clinical manifestation of schistosomiasis (a case report).

机构信息

Department of Medicine, Faculty of Health Sciences, Aga Khan University Medical College, Nairobi, Kenya.

出版信息

Pan Afr Med J. 2022 Jul 7;42:187. doi: 10.11604/pamj.2022.42.187.34227. eCollection 2022.

Abstract

Schistosomiasis is caused by parasitic blood flukes. It is one of the neglected tropical diseases (NTDs) and has variable manifestations depending on the species involved. Eggs and not adult worms are mostly responsible for the resultant pathologies commonly involving the small intestines. Colon polyps resulting from schistosomiasis represent a rare entity despite the endemicity of Schistosoma mansoni in the tropical regions. Praziquantel is the mainstay of treatment. Case presentation is of a 28 year old male with complaints of bloating, mild abdominal pain and loose stools over two weeks.On examination, the patient´s abdomen was soft on palpation with a liver span of 8 cm and a non-palpable spleen. Preliminary tests included stool microscopy which was negative for ova and cysts, negative for stool H. pylori antigen. Colonoscopy revealed a polyp at the caecum and pan-colonic erosions. Microscopy of the polyp showed numerous schistosome ova. The indolent picture of this particular patient makes it a unique case as the likelihood of the diagnosis not being schistosomiasis is greater than other differential diagnoses. The take-home message is that a high index of suspicion is needed in the diagnosis of colonic polyps resulting from schistosomiasis as it presents with non-specific manifestations and inconclusive laboratory and endoscopic findings.

摘要

血吸虫病是由寄生性血吸虫引起的。它是被忽视的热带病(NTDs)之一,其临床表现因涉及的物种而异。引起相关病变的主要是虫卵,而不是成虫,这些病变通常涉及小肠。尽管曼氏血吸虫在热带地区流行,但由血吸虫病引起的结肠息肉仍然是一种罕见的疾病。吡喹酮是主要的治疗方法。病例介绍为一名 28 岁男性,主诉腹胀、轻度腹痛和两周来大便稀。体格检查时,患者腹部柔软,肝脏触诊 8cm,脾脏未触及。初步检查包括粪便显微镜检查,虫卵和囊肿均为阴性,粪便幽门螺杆菌抗原阴性。结肠镜检查显示盲肠有一个息肉和全结肠糜烂。息肉的显微镜检查显示有大量血吸虫卵。该患者的惰性表现使其成为一个独特的病例,因为诊断为血吸虫病的可能性大于其他鉴别诊断。这一案例的重要信息是,对于由血吸虫病引起的结肠息肉的诊断,需要高度怀疑,因为其表现为非特异性症状,且实验室和内镜检查结果不确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0eb/9508373/d06a3c108e97/PAMJ-42-187-g001.jpg

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