Miyai K, Ichihara K, Kondo K, Mori S
Clin Endocrinol (Oxf). 1986 Nov;25(5):549-54. doi: 10.1111/j.1365-2265.1986.tb03608.x.
A total of 10,550 'normal' adults (8450 men and 2100 women) in the general population were screened by a paired assay method for serum PRL and 40 subjects with hyperprolactinaemia (greater than 75 micrograms/l) were detected. Of these, five patients (three men and two women) with pituitary prolactinoma, one man with empty sella syndrome, 10 cases of 'big' prolactinaemia, seven pregnant women and 13 subjects with drug-induced hyperprolactinaemia were found. The patients with prolactinoma had few if any complaints (asymptomatic prolactinoma).
采用配对检测法对普通人群中总共10550名“正常”成年人(8450名男性和2100名女性)进行血清催乳素筛查,检测出40名高催乳素血症患者(大于75微克/升)。其中,发现5例垂体催乳素瘤患者(3名男性和2名女性),1例空蝶鞍综合征男性患者,10例“大”催乳素血症患者,7名孕妇以及13名药物性高催乳素血症患者。催乳素瘤患者几乎没有任何症状(无症状催乳素瘤)。