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回顾性分析 2011-2020 年尼日利亚开展唇裂外展项目期间偶然发现的坏疽性口炎病例。

Retrospective Characterization of Noma Cases Found Incidentally across Nigeria during Outreach Programs for Cleft Lip from 2011-2020.

机构信息

Oral Health Advocacy Initiative, Abuja, FCT, Nigeria.

Department of Medical Microbiology and Parasitology, National Hospital Abuja, Abuja, Nigeria.

出版信息

Am J Trop Med Hyg. 2022 Oct 10;107(5):1132-1136. doi: 10.4269/ajtmh.22-0388. Print 2022 Nov 14.

Abstract

Reports of cases of noma in Nigeria remain scarce despite its known and devastating effects on victims. This report presents a retrospective cross-sectional study based on data regarding on patients with noma encountered incidentally during Oral Health Advocacy Initiative outreach on orofacial diseases across 34 states and the Federal Capital Territory in Nigeria over 10 years (2011-2020), which was aimed at contributing to an understanding of the epidemiology of noma in Nigeria. The data were collated and analyzed, and are presented in frequency distribution tables and charts. A total of 7,195 patients with noma were encountered. The northeastern region had the greatest number of patients (n = 1,785, 24.8%) whereas the southwestern region had the least (n = 196, 2.7%). When aggregated by state, Ondo State had the least number of patients (n = 31, 0.4%) whereas Kano State had the greatest (n = 623, 8.7%). Patient age ranged from 3 to 70 years, with a slight male preponderance (56.9%). This report highlights the fact that noma is prevalent in Nigeria but remains neglected, with extensive but preventable physical, emotional, and social debilitation and devastation of the victims across all age groups. There is a need for a more robust survey to determine the true burden of the disease. There is also an urgent need for collaboration between governments and nongovernmental organizations to institute appropriate interventions by way of public education and enlightenment, as well as case detection and early treatment to mitigate the devastating consequences of delayed or poorly managed cases.

摘要

尽管坏死性口炎对患者有已知的毁灭性影响,但尼日利亚关于该病的报告仍然很少。本报告介绍了一项回顾性横断面研究,该研究基于在尼日利亚 34 个州和联邦首都地区开展口腔健康宣传活动中偶然发现的坏死性口炎患者的数据,这些数据来自于 10 年来(2011-2020 年)对口腔疾病的调查,旨在帮助了解尼日利亚坏死性口炎的流行病学。对数据进行了整理和分析,并以频率分布表和图表的形式呈现。共发现 7195 例坏死性口炎患者。东北部地区的患者最多(n = 1785,24.8%),西南部地区的患者最少(n = 196,2.7%)。按州汇总时,翁多州的患者最少(n = 31,0.4%),而卡诺州的患者最多(n = 623,8.7%)。患者年龄在 3 至 70 岁之间,男性略多(56.9%)。本报告强调了这样一个事实,即坏死性口炎在尼日利亚很普遍,但仍被忽视,所有年龄段的患者都遭受了广泛但可预防的身体、情感和社会残疾和破坏。需要进行更有力的调查,以确定疾病的真实负担。政府和非政府组织之间也迫切需要合作,通过公共教育和宣传,以及病例发现和早期治疗,来实施适当的干预措施,以减轻延误或管理不善的病例的破坏性后果。

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