Evering T, Weiss L M
Department of Medicine (Division of Infectious Diseases), Albert Einstein College of Medicine, Bronx, New York 10461, USA.
Parasite Immunol. 2006 Nov;28(11):549-65. doi: 10.1111/j.1365-3024.2006.00886.x.
Immune compromise can modify the severity and manifestation of some parasitic infections. More widespread use of newer immnosuppressive therapies, the growing population of individuals with immunocompromised states as well as the prolonged survival of these patients have altered the pattern of parasitic infection. This review article discusses the burden and immunology of parasitic infections in patients who are immunocompromised secondary to congenital immunodeficiency, malnutrition, malignancy, and immunosuppressive medications. This review does not address the literature on parasitic infections in the setting of HIV-1 infection.
免疫功能受损可改变某些寄生虫感染的严重程度和表现形式。新型免疫抑制疗法的更广泛应用、免疫功能受损个体数量的不断增加以及这些患者生存期的延长,改变了寄生虫感染的模式。这篇综述文章讨论了因先天性免疫缺陷、营养不良、恶性肿瘤和免疫抑制药物导致免疫功能受损的患者中寄生虫感染的负担和免疫学。本综述未涉及关于HIV-1感染情况下寄生虫感染的文献。