牙周再生用生物材料。
Biomaterials for Periodontal Regeneration.
机构信息
Department of Biomedical Sciences, Texas A&M University College of Dentistry, 3302 Gaston Avenue, Dallas, TX 75246, USA.
Department of Biomedical Sciences, Texas A&M University College of Dentistry, 3302 Gaston Avenue, Dallas, TX 75246, USA.
出版信息
Dent Clin North Am. 2022 Oct;66(4):659-672. doi: 10.1016/j.cden.2022.05.011. Epub 2022 Sep 11.
As a widespread chronical disease, periodontitis progressively destroys tooth-supporting structures (periodontium) and eventually leads to tooth loss. Therefore, regeneration of damaged/lost periodontal tissues has been a major subject in periodontal research. During periodontal tissue regeneration, biomaterials play pivotal roles in improving the outcome of the periodontal therapy. With the advancement of biomaterial science and engineering in recent years, new biomimetic materials and scaffolding fabrication technologies have been proposed for periodontal tissue regeneration. This article summarizes recent progress in periodontal tissue regeneration from a biomaterial perspective. First, various guide tissue regeneration/guide bone regeneration membranes and grafting biomaterials for periodontal tissue regeneration are overviewed. Next, the recent development of multifunctional scaffolding biomaterials for alveolar bone/periodontal ligament/cementum regeneration is summarized. Finally, clinical care points and perspectives on the use of biomimetic scaffolding materials to reconstruct the hierarchical periodontal tissues are provided.
作为一种广泛存在的慢性疾病，牙周炎会逐渐破坏牙齿支撑结构（牙周组织），最终导致牙齿脱落。因此，受损/缺失牙周组织的再生一直是牙周研究的主要课题。在牙周组织再生过程中，生物材料在改善牙周治疗效果方面起着关键作用。近年来，随着生物材料科学和工程学的进步，已经提出了用于牙周组织再生的新型仿生材料和支架制造技术。本文从生物材料的角度综述了牙周组织再生的最新进展。首先，概述了用于牙周组织再生的各种引导组织再生/引导骨再生膜和移植生物材料。接下来，总结了用于牙槽骨/牙周韧带/牙骨质再生的多功能支架生物材料的最新进展。最后，提供了使用仿生支架材料重建分层牙周组织的临床护理要点和展望。
Zotero 插件