Hedlund R, Lindgren U, Ahlbom A
Clin Orthop Relat Res. 1987 Sep(222):132-9.
The risk of fracturing the proximal femur is high for individuals with metabolic bone disease or with low bone mass associated with advanced age. Incidences of 20,538 trochanteric and femoral neck fractures in adult Swedish men and women, from a computerized medical information register for all hospitals in Stockholm County, were analyzed for age- and sex-dependence. The rate of increase in the occurrence of fracture was nearly constant for both sexes, exponentially increasing with age for men over 20 years old and for women over 30 years old. The incidence of trochanteric and femoral neck fracture for men doubled every 7.8 and 7.0 years, respectively. The doubling rate of fracture incidence for premenopausal women, aged 30 to 49 years, did not significantly differ from that for postmenopausal women, aged 50 to 69 years. These findings suggest that age-associated factors common to both sexes provide the main risk for fracturing the proximal femur. Menopause does not pose a major risk.
患有代谢性骨病或因高龄导致骨量低的个体,股骨近端骨折风险较高。利用斯德哥尔摩郡所有医院的计算机化医疗信息登记系统,分析了瑞典成年男性和女性中20538例转子间骨折和股骨颈骨折的发生率,以研究年龄和性别依赖性。骨折发生率的增长速率在两性中几乎是恒定的,20岁以上男性和30岁以上女性的骨折发生率随年龄呈指数增长。男性转子间骨折和股骨颈骨折的发生率分别每7.8年和7.0年翻一番。30至49岁绝经前女性的骨折发生率翻倍率与50至69岁绝经后女性相比,无显著差异。这些发现表明,两性共有的与年龄相关的因素是股骨近端骨折的主要风险因素。绝经并非主要风险因素。