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1例与系统性红斑狼疮相关的呈脓疱表现的栅栏状中性粒细胞和肉芽肿性皮炎。

A case of palisaded neutrophilic and granulomatous dermatitis associated with systemic lupus erythematosus presenting with pustules.

作者信息

Tajima Aki, Yamazaki Fumikazu, Huynh Trang Nguyen Mai, Ueda-Hayakawa Ikuko, Kishimoto Izumi, Itsukage Shizu, Kume Noriko, Tanizaki Hideaki

机构信息

Department of Dermatology, Kansai Medical University, Hirakata-City, Japan.

Department of Dermatology, Osaka University, Osaka, Japan.

出版信息

J Dermatol. 2023 Feb;50(2):262-265. doi: 10.1111/1346-8138.16605. Epub 2022 Oct 11.

Abstract

Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a relatively rare skin disease that is characterized by a reactive granulomatous histopathological pattern and is often associated with systemic autoimmune diseases. We encountered a case of PNGD that presented with pustules, although the prototypical clinical presentation of PNGD is mainly erythema and papules. Here, this rare case of PNGD with pustules is presented and discussed in relation to the relevant literature.

摘要

栅栏状中性粒细胞和肉芽肿性皮炎(PNGD)是一种相对罕见的皮肤病,其特征为具有反应性肉芽肿性组织病理学模式,且常与系统性自身免疫性疾病相关。我们遇到了一例以脓疱为表现的PNGD病例,尽管PNGD的典型临床表现主要为红斑和丘疹。在此,呈现这例罕见的伴有脓疱的PNGD病例,并结合相关文献进行讨论。

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