Andonopoulos A P, Asimakopoulos G, Mallioris C, Karatza C, Skopa C
Clin Rheumatol. 1987 Jun;6(2):192-6. doi: 10.1007/BF02201023.
Five cases of sarcoidosis were identified among twenty cases of erythema nodosum, admitted to the Department of Medicine, during a two-year period. The clinical picture was dominated by hilar adenopathy and erythema nodosum in all cases. All five patients had gastrocnemius muscle biopsy performed, which revealed noncaseating epithelioid granuloma in four. Diagnosis in the fifth patient was made by transbronchial lung biopsy. The present study suggests, that gastrocnemius muscle biopsy might be considered as the initial diagnostic procedure of choice in this, more commonly seen in Caucasians, syndrome of sarcoidosis, presenting with hilar adenopathy and erythema nodosum, based on its safety, ease of performance and relatively high sensitivity and specificity.
在两年期间，医学科收治的20例结节性红斑患者中确诊了5例结节病。所有病例的临床表现均以肺门淋巴结肿大和结节性红斑为主。所有5例患者均进行了腓肠肌活检，其中4例显示非干酪样上皮样肉芽肿。第5例患者通过经支气管肺活检确诊。本研究表明，对于这种在白种人中更常见、以肺门淋巴结肿大和结节性红斑为表现的结节病综合征，基于其安全性、操作简便性以及相对较高的敏感性和特异性，腓肠肌活检可被视为首选的初始诊断方法。
