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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Venturelli F, Roscetti G, Roda L G

Comp Biochem Physiol B. 1987;87(3):485-8. doi: 10.1016/0305-0491(87)90041-1.

The role of the enkephalin-protecting plasma substances in the protection of non-opioid peptides from enzyme hydrolysis has been studied in laboratory animals and in man. 2. The results obtained indicate that all the peptides hydrolyzed by the plasma enzymes are also protected from the hydrolysis by the enkephalin-protecting substances. 3. The protection is fairly uniform in all the species and for all the peptides examined. However, in the human species the protection of leucine enkephalin is considerably higher than the average. These results are discussed in terms of a possible differential inhibition of the different plasma aminopeptidases.

实验室动物和人体中已对脑啡肽保护血浆物质在保护非阿片肽免受酶水解方面的作用进行了研究。2. 所获结果表明，所有被血浆酶水解的肽也受到脑啡肽保护物质的保护而免受水解。3. 在所有物种以及所检测的所有肽中，这种保护作用相当一致。然而，在人类中，亮氨酸脑啡肽的保护作用明显高于平均水平。就不同血浆氨基肽酶可能存在的差异抑制作用对这些结果进行了讨论。

Venturelli F, Roscetti G, Roda L G

Comp Biochem Physiol B. 1987;87(3):485-8. doi: 10.1016/0305-0491(87)90041-1.

The role of the enkephalin-protecting plasma substances in the protection of non-opioid peptides from enzyme hydrolysis has been studied in laboratory animals and in man. 2. The results obtained indicate that all the peptides hydrolyzed by the plasma enzymes are also protected from the hydrolysis by the enkephalin-protecting substances. 3. The protection is fairly uniform in all the species and for all the peptides examined. However, in the human species the protection of leucine enkephalin is considerably higher than the average. These results are discussed in terms of a possible differential inhibition of the different plasma aminopeptidases.

实验室动物和人体中已对脑啡肽保护血浆物质在保护非阿片肽免受酶水解方面的作用进行了研究。2. 所获结果表明，所有被血浆酶水解的肽也受到脑啡肽保护物质的保护而免受水解。3. 在所有物种以及所检测的所有肽中，这种保护作用相当一致。然而，在人类中，亮氨酸脑啡肽的保护作用明显高于平均水平。就不同血浆氨基肽酶可能存在的差异抑制作用对这些结果进行了讨论。