Department of Sports Rehabilitation, Shanghai University of Sport, Shanghai 200438, China.
School of Physical Education and Training, Shanghai University of Sport, Shanghai 200438, China.
Ageing Res Rev. 2022 Dec;82:101741. doi: 10.1016/j.arr.2022.101741. Epub 2022 Oct 8.
Neurodegenerative diseases have become an important concern with the accelerated aging process. Tai Chi Quan (TCQ) has positive benefits for brain health and chronic diseases. The aim of this study was to summarize the protective effects of TCQ for motor function, cognition, quality of life, and mood in patients with neurodegenerative diseases.
A systematic search was conducted via PubMed database and the Web of Science core collection database until August 20, 2021. The available English systematic reviews, meta-analyses, and clinical trials were included. Two reviewers completed the screening and assessment process independently.
A total of 28 studies on Parkinson's disease, 21 on cognitive impairment, and 9 on multiple sclerosis met the included criteria. The study found that TCQ remarkably improved general motor function and balance, and prevented falls for Parkinson's disease. TCQ significantly improved global cognitive function for cognitive impairment. TCQ was likely safe and beneficial for multiple sclerosis as result of heterogeneous outcomes and small samples.
TCQ exercise can effectively improve the motor function, global cognitive function, and falls in patients with neurodegenerative diseases. However, the positive effects of TCQ on the quality of life and mood of patients with neurodegenerative diseases need further evidence.
神经退行性疾病随着老龄化进程的加速已成为一个重要关注点。太极拳（TCQ）对大脑健康和慢性病有积极的益处。本研究旨在总结 TCQ 对神经退行性疾病患者运动功能、认知、生活质量和情绪的保护作用。
通过 PubMed 数据库和 Web of Science 核心合集数据库进行系统检索，截至 2021 年 8 月 20 日。纳入了现有的英文系统评价、荟萃分析和临床试验。两位评审员独立完成了筛选和评估过程。
共有 28 项关于帕金森病、21 项关于认知障碍和 9 项关于多发性硬化症的研究符合纳入标准。研究发现，TCQ 显著改善了帕金森病的一般运动功能和平衡，并预防了跌倒。TCQ 显著改善了认知障碍的整体认知功能。由于结果存在异质性且样本量较小，TCQ 对多发性硬化症可能是安全且有益的。
TCQ 运动可以有效改善神经退行性疾病患者的运动功能、整体认知功能和跌倒。然而，TCQ 对神经退行性疾病患者生活质量和情绪的积极影响需要进一步的证据。
