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[食管癌的放射治疗。通过放射学、内镜检查、活检及尸检进行临床结果核查]

[Radiotherapy of esophageal carcinoma. Results checked clinically by radiology, endoscopy, biopsy and autopsy].

作者信息

Schwegler N, Schlossberg D, Fehr H

出版信息

Dtsch Med Wochenschr. 1987 Aug 28;112(35):1330-5. doi: 10.1055/s-2008-1068244.

Abstract

Forty-four patients with histologically confirmed esophageal cancer were irradiated with 60 Gy, checked endoscopically and by biopsy, and then followed clinically or radiologically until their death. The findings confirm the local destructibility of esophageal cancer with loosely ionized radiation and a favorable effect on quality of life. Three quarters of the patients were able to take normal food at the end of the radiotherapy, while the remainder were at least able to swallow soft foods. Radiotherapy can be offered as an effective alternative to patients, especially when operation is associated with a high risk. This is also demonstrated by the fact that 23 of 32 patients who had endoscopy and biopsy again at the end of the radiotherapy had no histologically demonstrable tumor.

摘要

44例经组织学确诊的食管癌患者接受了60 Gy的放射治疗,通过内镜检查和活检进行检查,然后进行临床或放射学随访直至死亡。研究结果证实了食管癌对低电离辐射具有局部可破坏作用,且对生活质量有积极影响。四分之三的患者在放疗结束时能够正常进食,其余患者至少能够吞咽软食。放疗可以作为患者的一种有效替代方案,尤其是在手术风险较高的情况下。放疗结束时再次进行内镜检查和活检的32例患者中有23例在组织学上未发现肿瘤,这一事实也证明了这一点。

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