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评估阴道子宫切除术联合阴道网片固定术对微创骶棘韧带固定术的手术效果和并发症的影响。

Assessing the Impact of Vaginal Hysterectomy with Vaginal Mesh Attachment on Outcomes and Complications during Minimally Invasive Sacrocolpopexy.

作者信息

Woodburn Katherine L, Bradley Sarah E, Ward Sarah A, Schirm Karen A, Clarke Bayley, Gutman Robert E, Sokol Andrew I

机构信息

Section of Female Pelvic Medicine and Reconstructive Surgery.

Section of Female Pelvic Medicine and Reconstructive Surgery; Georgetown University/MedStar Washington Hospital Center, Washington, District of Columbia, Mission Health, Asheville, North Carolina; Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, Massachusetts.

出版信息

J Minim Invasive Gynecol. 2023 Jan;30(1):25-31. doi: 10.1016/j.jmig.2022.09.556. Epub 2022 Oct 9.

Abstract

STUDY OBJECTIVE

To compare mesh complications and failure rates after 1 year in laparoscopic minimally invasive sacrocolpopexy (MISC) with ultralightweight mesh attached vaginally during total vaginal hysterectomy (TVH), laparoscopically if posthysterectomy (PH), or laparoscopically during supracervical hysterectomy.

DESIGN

Single-center retrospective cohort study.

SETTING

Tertiary referral center.

PATIENTS

Women with symptomatic pelvic organ prolapse who elected for MISC.

INTERVENTIONS

Laparoscopic MISC with ultralightweight mesh attached vaginally during TVH, laparoscopically if PH, or laparoscopically during supracervical hysterectomy. Composite failure was defined as recurrent prolapse symptoms, prolapse past the hymen, or retreatment for prolapse.

MEASUREMENTS AND MAIN RESULTS

Between 2010 and 2017, 650 patients met the inclusion criteria with 278 PH, 82 supracervical hysterectomy, and 290 vaginal hysterectomy patients. Median follow-up was similar for all groups (382 days vs 379 vs 345; p = .31). The majority in all groups were white (66.6%), nonsmokers (74.8%), postmenopausal (82.5%), and did not use estrogen (70.3%). Mesh complications did not differ among groups (1.6% PH, 2.5% supracervical hysterectomy, 2.2% vaginal hysterectomy; p >.99). There was no difference in anatomic failure (5% PH, 1.2% supracervical hysterectomy, 2.1% vaginal hysterectomy; p = .07), reoperation for prolapse (1.4% vs 1.2% vs 0.7%; p = .57), or composite failure (9.0% vs 3.7% vs 4.8%; p = .07).

CONCLUSIONS

TVH with vaginal mesh attachment of ultralightweight mesh had similar adverse events, mesh exposure rates, and failure rates to those of laparoscopic PH sacrocolpopexy or supracervical hysterectomy with laparoscopic mesh attachment.

摘要

研究目的

比较在全子宫切除术(TVH)期间经阴道附着超轻量网片进行腹腔镜微创骶骨阴道固定术(MISC)、子宫切除术后(PH)经腹腔镜或在次全子宫切除术中经腹腔镜进行该手术1年后的网片并发症和失败率。

设计

单中心回顾性队列研究。

地点

三级转诊中心。

患者

选择进行MISC的有症状盆腔器官脱垂女性。

干预措施

在TVH期间经阴道附着超轻量网片进行腹腔镜MISC,PH时经腹腔镜进行,或在次全子宫切除术中经腹腔镜进行。复合失败定义为复发的脱垂症状、脱垂超过处女膜或因脱垂再次治疗。

测量指标及主要结果

2010年至2017年期间,650例患者符合纳入标准,其中278例为子宫切除术后患者,82例为次全子宫切除术患者,290例为全子宫切除术患者。所有组的中位随访时间相似(382天对379天对345天;p = 0.31)。所有组中的大多数患者为白人(66.6%)、非吸烟者(74.8%)、绝经后(82.5%)且未使用雌激素(70.3%)。各组间网片并发症无差异(子宫切除术后为1.6%,次全子宫切除术为2.5%,全子宫切除术为2.2%;p > 0.99)。解剖学失败(子宫切除术后为5%,次全子宫切除术为1.2%,全子宫切除术为2.1%;p = 0.07)、因脱垂再次手术(1.4%对1.2%对0.7%;p = 0.57)或复合失败(9.0%对3.7%对4.8%;p = 0.07)方面均无差异。

结论

经阴道附着超轻量网片的TVH与经腹腔镜进行子宫切除术后骶骨阴道固定术或经腹腔镜附着网片的次全子宫切除术相比,不良事件、网片暴露率和失败率相似。

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