Kikuchi Jacqueline Y, Yanek Lisa R, Handa Victoria L, Chen Chi Chiung Grace, Jacobs Stephanie, Blomquist Joan, Patterson Danielle
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, 4940 Eastern Ave, 301 Building, Suite 3200, Baltimore, MD, 21224, USA.
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Int Urogynecol J. 2023 Jan;34(1):135-145. doi: 10.1007/s00192-022-05263-w. Epub 2022 Jun 11.
Sacrocolpopexy is effective for apical prolapse repair and is often performed with hysterectomy. It is unknown whether supracervical or total hysterectomy at time of sacrocolpopexy influences prolapse recurrence and mesh complications. The primary objective of this study is to compare reoperations for recurrent prolapse after sacrocolpopexy with either supracervical hysterectomy or total hysterectomy, or without concomitant hysterectomy. We also sought to compare these three groups for the incidence of mesh complications and describe cervical interventions following supracervical hysterectomy.
A retrospective cohort study of sacrocolpopexy was performed using the MarketScan® Research Database. Women > 18 years who underwent sacrocolpopexy between 2010 to 2014 were identified. Utilizing diagnostic and procedural codes, reoperations for prolapse and mesh complications were identified. Women with < 2 years of follow-up were excluded.
From 2010 to 2014, 3463 women underwent sacrocolpopexy with at least 2 years of follow-up, 910 (26.3%) with supracervical hysterectomy, 1243 (35.9%) with total hysterectomy, and 1310 (37.8%) without hysterectomy. Reoperations for prolapse were similar after supracervical hysterectomy (1.5%), after total hysterectomy (1.1%, p = 0.40), and without hysterectomy (1.5%, p = 0.98). Mesh complications after sacrocolpopexy were similar after supracervical hysterectomy (1.8%), after total hysterectomy (1.5%, p = 0.68), and without hysterectomy (2.8%, p = 0.11). Following supracervical hysterectomy, 0.9% underwent cervical procedures.
When comparing supracervical and total hysterectomy at time of sacrocolpopexy, there were no significant differences in reoperations for recurrent prolapse, reoperations for mesh complications, or mesh complication diagnoses. This study shows that surgeons can be reassured on performing hysterectomy with sacrocolpopexy.
骶骨阴道固定术对修复顶端脱垂有效,且常与子宫切除术同时进行。骶骨阴道固定术时行次全子宫切除术还是全子宫切除术是否会影响脱垂复发及网片并发症尚不清楚。本研究的主要目的是比较骶骨阴道固定术联合次全子宫切除术、全子宫切除术或不伴子宫切除术时复发性脱垂再次手术的情况。我们还试图比较这三组的网片并发症发生率,并描述次全子宫切除术后的宫颈干预情况。
使用MarketScan®研究数据库对骶骨阴道固定术进行回顾性队列研究。确定2010年至2014年间接受骶骨阴道固定术的18岁以上女性。利用诊断和手术编码确定脱垂和网片并发症的再次手术情况。随访时间不足2年的女性被排除。
2010年至2014年,3463名女性接受了至少2年随访的骶骨阴道固定术,910名(26.3%)行次全子宫切除术,1243名(35.9%)行全子宫切除术,1310名(37.8%)未行子宫切除术。次全子宫切除术后脱垂再次手术率(1.5%)、全子宫切除术后(1.1%,p = 0.40)和未行子宫切除术后(1.5%,p = 0.98)相似。骶骨阴道固定术后网片并发症在次全子宫切除术后(1.8%)、全子宫切除术后(1.5%,p = 0.68)和未行子宫切除术后(2.8%,p = 0.11)相似。次全子宫切除术后,0.9%的患者接受了宫颈手术。
比较骶骨阴道固定术时的次全子宫切除术和全子宫切除术,复发性脱垂再次手术、网片并发症再次手术或网片并发症诊断方面无显著差异。本研究表明,外科医生在进行骶骨阴道固定术时可放心地行子宫切除术。