Dallas Kai, Taich Lior, Kuhlmann Paige, Rogo-Gupta Lisa, Eilber Karyn, Anger Jennifer T, Scott Victoria
Department of Surgery, Division of Urology, Cedars-Sinai Medical Center, Los Angeles, California.
Department of Obstetrics & Gynecology, Stanford University School of Medicine, Stanford, California.
J Urol. 2022 Mar;207(3):669-676. doi: 10.1097/JU.0000000000002262. Epub 2021 Oct 25.
Although minimally invasive (robotic or laparoscopic) abdominal sacrocolpopexy (MISC) has become the new gold standard for durable pelvic organ prolapse repair after the vaginal mesh controversy, current literature is limited. Our objective was to study reoperation for mesh complications after MISC.
All women undergoing MISC in California from January 2012 to December 2018 were identified from Office of Statewide Health Planning and Development data sets using appropriate ICD-9/10 (International Classification of Diseases 9th/10th Revision) and CPT® (Current Procedural Terminology) codes. Univariate and multivariable analyses were performed to assess associations between patient demographics, surgical details and our primary outcomes: rates of reoperation for a mesh complication.
Of 12,189 women undergoing MISC 8,398 (68.9%) had concomitant hysterectomy. Total hysterectomy (TH) and supracervical hysterectomy (SCH) were performed in 5,027 (41.2%) and 3,371 (27.6%) cases, respectively. Reoperation rates for mesh complications were lower after SCH vs TH (overall: 0.7%, mean followup time 1,111 days vs 3.1%, mean followup time 1,095 days, p <0.001; subcohort with at least 4 years of followup: 2.1% vs 8.9%, p <0.001). Additionally, mesh complication rates were higher even if TH was performed remotely, as compared to concomitant SCH (5.2% vs 0.7%, p <0.001). The increased risk for reoperation due to mesh complications after TH was preserved on multivariable analysis (OR 4.20, 95% CI 2.72‒6.50, p <0.001).
Concomitant TH at time of MISC is associated with a significantly higher rate of mesh complication as compared to SCH. The increased risk of a mesh complication associated with TH is present even if the TH was performed prior to the MISC.
尽管在阴道网片引发争议后,微创(机器人或腹腔镜)腹骶骨固定术(MISC)已成为持久治疗盆腔器官脱垂的新金标准,但目前的文献有限。我们的目的是研究MISC术后因网片并发症而进行的再次手术。
利用适当的ICD-9/10(国际疾病分类第9版/第10版)和CPT®(现行程序术语)编码,从全州卫生规划与发展办公室的数据集中识别出2012年1月至2018年12月在加利福尼亚州接受MISC手术的所有女性。进行单因素和多因素分析,以评估患者人口统计学、手术细节与我们的主要结局之间的关联:因网片并发症而进行再次手术的发生率。
在12189例接受MISC手术的女性中,8398例(68.9%)同时进行了子宫切除术。全子宫切除术(TH)和次全子宫切除术(SCH)分别进行了5027例(41.2%)和3371例(27.6%)。与TH相比,SCH术后因网片并发症而进行再次手术的发生率较低(总体:0.7%,平均随访时间1111天;3.1%,平均随访时间1095天,p<0.001;至少随访4年的亚组:2.1%对8.9%,p<0.001)。此外,与同期进行SCH相比,即使远程进行TH,网片并发症发生率也更高(5.2%对0.7%,p<0.001)。多因素分析显示,TH术后因网片并发症而进行再次手术的风险增加(OR 4.20,95%CI 2.72-6.50,p<0.001)。
与SCH相比,MISC手术时同期进行TH与网片并发症发生率显著升高相关。即使TH在MISC之前进行,与TH相关的网片并发症风险增加仍然存在。