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伊布替尼治疗期间霍奇金淋巴瘤型里氏转化:一例病例报告及文献复习

Hodgkin's variant of Richter transformation during ibrutinib therapy: A case report and review of the literature.

作者信息

Afonso Carolina, Gomes Marília, Pereira Marta Isabel, Faria Carlos, Pina Raquel, Saraiva Tiago, Geraldes Catarina, Carda José Pedro

机构信息

Department of Hematology Hospitais da Universidade de Coimbra, Centro Hospitalar e Universitário de Coimbra Coimbra Portugal.

Faculty of Medicine University of Coimbra Coimbra Portugal.

出版信息

Clin Case Rep. 2022 Oct 3;10(10):e6136. doi: 10.1002/ccr3.6136. eCollection 2022 Oct.

Abstract

Hodgkin's variant of Richter transformation is a rare complication of chronic lymphocytic leukemia and is associated with inferior outcomes compared to de novo Hodgkin lymphoma. Further data concerning prognosis and treatment of Hodgkin's variant of Richter transformation occurring in the setting of novel targeted therapies are needed.

摘要

霍奇金淋巴瘤型里氏转化是慢性淋巴细胞白血病的一种罕见并发症,与原发性霍奇金淋巴瘤相比,其预后较差。对于在新型靶向治疗背景下发生的霍奇金淋巴瘤型里氏转化,还需要更多关于其预后和治疗的数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfb5/9529751/4e69763ad8fc/CCR3-10-e6136-g002.jpg

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