Fakhra Sadaf, Javaid Awad, Shafi Amaan, Ahsan Chowdhury
Kirk Kerkorian School of Medicine at UNLV, 2040 W. Charleston Blvd., 3rd Floor, Las Vegas, NV, 89102, USA.
Eur Heart J Case Rep. 2022 Sep 23;6(10):ytac394. doi: 10.1093/ehjcr/ytac394. eCollection 2022 Oct.
Patients with a bicuspid aortic valve have increased risk of infective endocarditis, but common organisms are not always the culprit. We describe a case of an otherwise healthy young gentleman with bicuspid aortic valve who experienced endocarditis. The aim of this case report is to highlight an uncommon cause of endocarditis associated with significant morbidity and mortality in order to improve the care provided by trainees and clinicians.
A 37-year-old male presented with a 1-month history of fever, weight loss, myalgia, and night sweats. On transoesophageal echocardiography, he was found to have a bicuspid aortic valve with large vegetation and severe aortic insufficiency. Blood cultures were positive for . The endocarditis was successfully treated with surgical aortic valve replacement and 6 weeks of antibiotic therapy.
Bicuspid valves are known to have increased susceptibility to endocarditis. The difficulty of isolating typically leads to delayed diagnosis and significant complications. This case is a reminder to have a high degree of suspicion for organisms which are rare and difficult to isolate because prompt recognition and surgical intervention may improve the outcome of care.
二叶式主动脉瓣患者感染性心内膜炎的风险增加，但常见病原体并不总是罪魁祸首。我们描述了一例患有二叶式主动脉瓣的健康年轻男性发生心内膜炎的病例。本病例报告的目的是强调一种与高发病率和死亡率相关的心内膜炎罕见病因，以改善实习医生和临床医生提供的护理。
一名37岁男性，有1个月的发热、体重减轻、肌痛和盗汗病史。经食管超声心动图检查发现他有二叶式主动脉瓣，伴有大的赘生物和严重的主动脉瓣关闭不全。血培养 呈阳性。通过手术置换主动脉瓣和6周的抗生素治疗，心内膜炎得到成功治疗。
已知二叶式瓣膜患心内膜炎的易感性增加。分离 的困难通常导致诊断延迟和严重并发症。本病例提醒我们要高度怀疑罕见且难以分离的病原体，因为及时识别和手术干预可能改善护理结果。
