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缺陷嗜养菌性心内膜炎——诊断与治疗挑战:病例报告

Abiotrophia defectiva endocarditis - Diagnostic and therapeutic challenge: Case report.

作者信息

Wilawer Małgorzata, Elikowski Waldemar, Greberski Krzysztof, Ratajska Paulina Anna, Welc Natalia Anna, Lisiecka Monika Ewa

机构信息

Department of Internal Medicine, Józef Struś Hospital, Poznań, Poland.

Department of Cardiac Surgery, Józef Struś Hospital, Poznan, Poland.

出版信息

IDCases. 2023 Oct 8;34:e01906. doi: 10.1016/j.idcr.2023.e01906. eCollection 2023.

DOI:10.1016/j.idcr.2023.e01906
PMID:37867569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10585279/
Abstract

Belonging to the normal oral, gastrointestinal, and urogenital flora, is responsible for 1-2 % of all infective endocarditis (IE) cases. The manifestation of endocarditis may by atypical, without fever. Difficult to isolate pathogen requires special culture media. A 45-year-old female was admitted due to anemia and progressive weight loss (8 kg in 6 months). She had a history of benign mitral valve (MV) prolapse and non-stenotic bicuspid aortic valve (BAV). In echocardiography, large vegetations on MV and small vegetation on BAV were found. An enriched medium for fastidious pathogens was used. was identified using biochemical analysis with VITEK-2 Compact. In the fourth week of antibiotic therapy, she required urgent MV replacement due to MV regurgitation progression while vegetation on BAV disappeared. Although patient's frailty and underweight caused prolonged postoperative wound healing, she was transferred to rehabilitation in good conditions. No relapse of IE was observed during five-month follow-up.

摘要

属于正常口腔、胃肠道和泌尿生殖系统菌群,占所有感染性心内膜炎(IE)病例的1-2%。心内膜炎的表现可能不典型,无发热。难以分离出病原体需要特殊的培养基。一名45岁女性因贫血和进行性体重减轻(6个月内减轻8公斤)入院。她有良性二尖瓣脱垂和非狭窄性二叶主动脉瓣病史。超声心动图检查发现二尖瓣上有大的赘生物,主动脉瓣上有小的赘生物。使用了用于苛求病原体的富集培养基。通过VITEK-2 Compact生化分析进行鉴定。在抗生素治疗的第四周,由于二尖瓣反流进展,她需要紧急进行二尖瓣置换,而主动脉瓣上的赘生物消失。尽管患者身体虚弱且体重过轻导致术后伤口愈合时间延长,但她情况良好地转入康复阶段。在五个月的随访中未观察到感染性心内膜炎复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1912/10585279/81a3511255c1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1912/10585279/b6ffb26fb794/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1912/10585279/81a3511255c1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1912/10585279/b6ffb26fb794/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1912/10585279/81a3511255c1/gr2.jpg

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Front Pediatr. 2022 Jul 6;10:894049. doi: 10.3389/fped.2022.894049. eCollection 2022.
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Infective endocarditis and oral health-a Narrative Review.
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Clin Case Rep. 2025 Apr 6;13(4):e70400. doi: 10.1002/ccr3.70400. eCollection 2025 Apr.
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