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巨大、侵袭性且具有破坏性的主动脉瓣及主动脉壁心内膜炎:一例儿童紧急但成功的Ross-Konno手术病例报告

Huge, invasive, and destructive endocarditis of the aortic valve and the aortic wall: a case report of an emergency but successful Ross-Konno operation in a child.

作者信息

Cetera Vera, Cantinotti Massimiliano, Barberi Elisa, Pak Vitali

机构信息

Fondazione Toscana Gabriele Monasterio, Heart Hospital, Via Aurelia Sud, Massa 54100, Italy.

出版信息

Eur Heart J Case Rep. 2024 Jul 23;8(8):ytae356. doi: 10.1093/ehjcr/ytae356. eCollection 2024 Aug.

Abstract

BACKGROUND

forms Gram-positive cocci, is part of normal oropharyngeal and gastrointestinal flora, and is rarely involved in endocarditis in children population. Its special nutritional requirements and subacute clinical course may delay diagnosis and proper treatment, leading to life-threatening consequences.

CASE SUMMARY

We report a rare case of huge and destructive infective endocarditis (IE) of the aortic valve and the aortic wall in a 3-year-old child, in follow-up after surgical valvuloplasty for congenital aortic stenosis. The child presented at our department with signs of left side hemiplegia. Transthoracic echocardiography showed severe aortic regurgitation due to large vegetation extending to the aortic wall up to the aortic arch. Blood cultures resulted positive for . He was initially treated conservatively with antibiotic therapy. Ten days after admission, because of clinical deterioration, he required intubation and an emergency Ross-Konno operation. Despite the critical conditions and highly risky surgery, the child recovered well and was discharged home 5 weeks after the operation.

DISCUSSION

IE is rare in children. Since 1995, only 16 cases of IE have been reported in children, including our case. This pathogen has a higher rate of complications when affecting children rather than adult population. Our case demonstrates that conservative strategy with antibiotics is rarely resolutive in the case of IE caused by . Whenever one or more indications for surgery are present, surgical intervention should always be taken into consideration, even if clinical conditions are prohibitive and surgery is at very high risk.

摘要

背景

形成革兰氏阳性球菌,是正常口咽和胃肠道菌群的一部分,在儿童人群中很少引起心内膜炎。其特殊的营养需求和亚急性临床病程可能会延迟诊断和适当治疗,从而导致危及生命的后果。

病例摘要

我们报告了一例罕见的3岁儿童巨大破坏性主动脉瓣和主动脉壁感染性心内膜炎(IE)病例,该患儿因先天性主动脉狭窄接受手术瓣膜成形术后进行随访。患儿因左侧偏瘫症状就诊于我科。经胸超声心动图显示,由于巨大赘生物延伸至主动脉壁直至主动脉弓,导致严重主动脉反流。血培养结果为……阳性。患儿最初接受抗生素保守治疗。入院10天后,由于临床病情恶化,需要插管并进行紧急罗斯-康诺手术。尽管病情危急且手术风险极高,但患儿恢复良好,术后5周出院。

讨论

IE在儿童中罕见。自1995年以来,包括我们的病例在内,儿童中仅报告了16例IE病例。这种病原体感染儿童时的并发症发生率高于成人。我们的病例表明,对于由……引起的IE,抗生素保守治疗很少能解决问题。只要存在一个或多个手术指征,即使临床情况不允许且手术风险极高,也应始终考虑手术干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/445e/11310689/7b81f3a74fa5/ytae356il1.jpg

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