Kato N
Exp Brain Res. 1987;67(1):119-26. doi: 10.1007/BF00269460.
The postnatal development of the striate cortical projection onto the extrageniculate visual thalamus was examined by using the orthograde and retrograde HRP methods. At birth, the projection is present, and fibres of the projection terminate in the lateral part of the lateral posterior nucleus. A rough topographical arrangement of the projection is already established. Neurones that give rise to the projection are located exclusively in layer V from birth onward. However, the neurones are much more densely packed at birth than in adult cats. The packing density of the neurones decreases rapidly during the second postnatal week, and afterwards continues to become gradually lower. In the meantime, the cross sectional area of the neurones increases sharply during the second postnatal week. These findings suggest that striate cortical neurones projecting onto the lateral posterior nucleus rapidly complete the final stages of their maturation shortly after the normal opening of the eyelids, and during this time some of these neurones undergo axonal elimination or neuronal death, or both.
运用顺行和逆行辣根过氧化物酶（HRP）法，研究了纹状皮质向膝外视觉丘脑投射的产后发育情况。出生时，这种投射就已存在，投射纤维终止于外侧后核的外侧部分。投射的大致拓扑排列已经形成。从出生起，产生这种投射的神经元仅位于第V层。然而，出生时神经元的密集程度远高于成年猫。出生后第二周，神经元的密集程度迅速降低，之后继续逐渐下降。与此同时，出生后第二周神经元的横截面积急剧增加。这些发现表明，投射到外侧后核的纹状皮质神经元在眼睑正常睁开后不久迅速完成其成熟的最后阶段，在此期间，其中一些神经元会发生轴突消除或神经元死亡，或两者皆有。
