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视觉胼胝体连接建立过程中轴突的生长与重塑。

Growth and reshaping of axons in the establishment of visual callosal connections.

作者信息

Innocenti G M

出版信息

Science. 1981 May 15;212(4496):824-7. doi: 10.1126/science.7221566.

DOI:10.1126/science.7221566
PMID:7221566
Abstract

The visual cortical areas in the two hemispheres are interconnected by axons running through the corpus callosum. In adult cats, these axons originate from, and terminate in, tangentially restricted portions of each area. In young kittens, however, callosal axons originate from the entire extent of each area, although they apparently enter the gray matter only in the restricted regions where they will also be found in adults. In kittens, but not in adults, callosal axons also reach other regions, but there they appear to be confined to the lowest part of layer VI. During the first two postnatal months, the callosal efferent zones become progressively restricted to their adult locations. During this process, many neurons eliminate the axons (or axon collaterals) that they had formerly sent through the corpus callosum and form permanent connection ipsilaterally.

摘要

两个半球的视觉皮层区域通过穿过胼胝体的轴突相互连接。在成年猫中,这些轴突起源于每个区域的切线受限部分,并终止于这些部分。然而,在幼小猫中,胼胝体轴突起源于每个区域的整个范围,尽管它们显然仅在成年时也会出现的受限区域进入灰质。在小猫而非成年猫中,胼胝体轴突也会到达其他区域,但在那里它们似乎局限于VI层的最下部。在出生后的头两个月,胼胝体传出区逐渐限制到其成年位置。在此过程中,许多神经元消除了它们以前通过胼胝体发出的轴突(或轴突侧支),并同侧形成永久连接。

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Growth and reshaping of axons in the establishment of visual callosal connections.视觉胼胝体连接建立过程中轴突的生长与重塑。
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