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循环免疫复合物对前列腺癌致敏白细胞体外反应性的抑制作用

Inhibition of sensitized leukocyte's in vitro reactivity by circulating immune complexes in prostate cancer.

作者信息

Bhatti R, Shaw M, Ray P

出版信息

Experientia. 1987 Aug 15;43(8):916-7. doi: 10.1007/BF01951666.

Abstract

Circulating immune complexes in the sera of patients with confirmed histological diagnosis of carcinoma of the prostate, were found to interfere in the sensitized leukocyte's in vitro reactivity to prostate cancer associated antigen as evaluated by tube leukocyte adherence inhibition assay, thereby suggesting an inhibitory role of such serum factors in host's anti tumor cell mediated immune responses.

摘要

在经组织学确诊为前列腺癌的患者血清中发现,循环免疫复合物会干扰致敏白细胞对前列腺癌相关抗原的体外反应性(通过试管白细胞黏附抑制试验评估),从而表明此类血清因子在宿主抗肿瘤细胞介导的免疫反应中具有抑制作用。

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