Stolbov A L
Fiziol Zh SSSR Im I M Sechenova. 1987 Jun;73(6):826-30.
Wistar rats were subjected to gradual blood replacement with albumin solution (hemodilution). Variation of oxygen tension (pO2) in the liver as well as parameters of oxygen transport in arterial and portal blood were measured. Tissue pO2 showed some increase after hematocrit dropped to 35-40% whereas tissue pO2 rapidly decreased after further dropping of the hematocrit. Hemoglobin saturation with oxygen grew in portal vein under moderate hemodilution. Left shift of the oxyhemoglobin dissociation curve and increase of the portal pO2 occurred simultaneously. These changes in portal blood could be a cause of the liver tissue pO2 increase in early steps of the hemodilution.
将Wistar大鼠用白蛋白溶液进行逐步血液置换（血液稀释）。测量肝脏中氧张力（pO2）的变化以及动脉血和门静脉血中的氧运输参数。血细胞比容降至35 - 40%后，组织pO2有所增加，而血细胞比容进一步下降后，组织pO2迅速降低。在适度血液稀释下，门静脉中氧合血红蛋白饱和度增加。氧合血红蛋白解离曲线左移和门静脉pO2增加同时发生。门静脉血中的这些变化可能是血液稀释早期肝脏组织pO2增加的原因。
