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锈管综合征:病例报告及文献复习。

Rusty pipe syndrome: a case report and review of the literature.

机构信息

Key Laboratory of Reproductive Genetics (Ministry of Education) and Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, Zhejiang, China.

Key Laboratory of Women's Reproductive Health Research of Zhejiang Province and Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, Zhejiang, China.

出版信息

BMC Pregnancy Childbirth. 2022 Oct 13;22(1):770. doi: 10.1186/s12884-022-05048-5.

Abstract

BACKGROUND

Painless bloody nipple discharge is often classified as pathological due to its association with malignant lesions. However, it can also be a completely harmless condition. Rusty pipe syndrome is a rare cause of benign, self-limiting bloody nipple discharge during late pregnancy and early lactation. Given that rusty pipe syndrome is not described in conventional textbooks, we thought it would be appropriate to bring this benign disease to the notice of readers.

CASE PRESENTATION

A 31-year-old G1P1 female delivered an infant with a birth weight of 3000 g via cesarean section at 39 weeks of gestation. The baby was admitted to the pediatric intensive care unit for a suspected oblique inguinal hernia. The mother had bilateral painless bloody nipple discharge when she started to express milk. A physical examination uncovered no signs of inflammation, engorgement, palpable mass, tenderness, cracks or ulcers. A breast ultrasound and cytological analysis revealed no signs of a neoplasm. Without any medical intervention, the color of the rusty milk changed from dark brown to light brown during hospitalization and finally resolved six days postpartum.

CONCLUSION

Rusty pipe syndrome is a self-limiting benign condition that should be considered in the differential diagnosis of bloody nipple discharge. Awareness of this rare disease by medical professionals would be extremely beneficial for avoiding unneeded examinations and discontinuity of exclusive breastfeeding.

摘要

背景

无痛血性乳头溢液常因其与恶性病变有关而被归类为病理性。然而,它也可能是一种完全无害的情况。锈管综合征是妊娠晚期和哺乳期早期良性、自限性血性乳头溢液的罕见原因。鉴于锈管综合征在传统教科书中并未描述,我们认为将这种良性疾病告知读者是合适的。

病例介绍

一位 31 岁 G1P1 的女性,孕 39 周时行剖宫产术娩出一 3000 克婴儿,婴儿因疑似斜疝被收入儿科重症监护病房。产妇开始泌乳时出现双侧无痛性血性乳头溢液。体格检查未发现炎症、充盈、可触及肿块、触痛、皲裂或溃疡。乳房超声和细胞学分析未发现肿瘤迹象。在没有任何医疗干预的情况下,住院期间锈色奶的颜色从深棕色变为浅棕色,最终在产后第 6 天消退。

结论

锈管综合征是一种自限性良性疾病,应在血性乳头溢液的鉴别诊断中考虑。医务人员对这种罕见疾病的认识将非常有利于避免不必要的检查和中断纯母乳喂养。

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