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乳房大肿块伴血性乳头溢液:良性导管内乳头状瘤。

Large breast lump with bloody nipple discharge: benign intraductal papilloma.

机构信息

Breast and Endocrine Unit, Department of Surgery, Hospital Raja Perempuan Zainab II, Kota Bharu, Malaysia

Breast and Endocrine Unit, Department of Surgery, Hospital Raja Perempuan Zainab II, Kota Bharu, Malaysia.

出版信息

BMJ Case Rep. 2020 Nov 4;13(11):e236818. doi: 10.1136/bcr-2020-236818.

DOI:10.1136/bcr-2020-236818
PMID:33148555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7643465/
Abstract

A 32-year-old woman presented with a 3 cm×3 cm left breast lump associated with bloody nipple discharge during her early pregnancy. Examination and ultrasonography showed benign features, whereas core needle biopsies revealed a benign papilloma. Six months after her delivery, a 6 cm×6 cm benign papilloma was completely excised via circumareolar incision. The majority of intraductal papillomas are small; however, they can also present as a large mass rarely. We should be wary of a malignant papillary lesion when there is the presence of atypia on core needle biopsy or imaging-histology discordance. A concordant benign papilloma with benign imaging findings is otherwise reassuring. Clinicians need to be aware of this uncommon presentation of large intraductal papilloma as a complete curative excision can be achieved through a cosmetically placed incision.

摘要

一位 32 岁女性在孕早期出现左乳 3cm×3cm 肿块,伴血性乳头溢液。检查和超声显示良性特征,而空心针活检显示良性乳突状瘤。产后 6 个月,通过乳晕缘切口完全切除 6cm×6cm 的良性乳突状瘤。大多数导管内乳突瘤较小;然而,它们也很少表现为大肿块。当空心针活检或影像学-组织学不一致存在不典型时,我们应该警惕恶性乳突状病变。如果影像学表现良性的一致性良性乳突状瘤则令人安心。临床医生需要意识到这种不常见的大导管内乳突状瘤表现,因为通过美容切口可以实现完全治愈性切除。

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2
Challenges in the management of giant intraductal breast papilloma.巨大导管内乳头状瘤的管理挑战
Clin Case Rep. 2015 Jan;3(1):7-10. doi: 10.1002/ccr3.116. Epub 2014 Nov 25.
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Nonmalignant breast papillary lesions at core-needle biopsy: a meta-analysis of underestimation and influencing factors.核心针活检中的非恶性乳腺乳头状病变:低估的荟萃分析及影响因素。
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