Hector-Center for Nutrition, Exercise and Sports, Department of Medicine 1, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, 91054 Erlangen, Germany.
German Center Immunotherapy (DZI), University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Int J Environ Res Public Health. 2022 Sep 28;19(19):12308. doi: 10.3390/ijerph191912308.
Initially, we aimed to investigate the impact of a one-year worksite low-volume, high-intensity interval training (LOW-HIIT) on cardiometabolic health in 114 sedentary office workers. Due to the COVID-19 pandemic outbreak, LOW-HIIT was discontinued after 6 months and participants were followed up for 6 months to analyze physical activity/exercise behavior and outcome changes during lockdown. Health examinations, including cardiopulmonary exercise testing and the assessment of cardiometabolic markers were performed baseline (T-1), after 6 months (T-2, termination of worksite LOW-HIIT) and 12 months (T-3, follow-up). Cycle ergometer LOW-HIIT (5 × 1 min at 85-95% HR) was performed 2×/week. For follow-up analyses, participants were classified into three groups: HIIT-group (continued home-based LOW-HIIT), EX-group (continued other home-based exercises), and NO-EX-group (discontinued LOW-HIIT/exercise). At T-2, VO (+1.5 mL/kg/min, = 0.002), mean arterial blood pressure (MAB, -4 mmHg, < 0.001), HbA (-0.2%, = 0.005) and self-reported quality of life (QoL, +5 points, < 0.001) were improved. At T-3, HIIT-group maintained VO and QoL and further improved MAB. EX-group maintained MAB and QoL but experienced a VO decrease. In NON-EX, VO, MAB and QoL deteriorated. We conclude that LOW-HIIT can be considered a promising option to improve cardiometabolic health in real-life conditions and to mitigate physical inactivity-related negative health impacts during lockdowns.
最初，我们旨在研究为期一年的工作场所低容量、高强度间歇训练（LOW-HIIT）对 114 名久坐不动的办公室工作人员的心脏代谢健康的影响。由于 COVID-19 大流行爆发，LOW-HIIT 在 6 个月后停止，参与者在封锁期间进行了 6 个月的随访，以分析身体活动/运动行为和结果的变化。健康检查包括心肺运动测试和心脏代谢标志物的评估，在基线（T-1）、6 个月后（T-2，工作场所 LOW-HIIT 结束）和 12 个月后（T-3，随访）进行。使用自行车测功计进行 LOW-HIIT（5×1 分钟，HR 为 85-95%），每周 2 次。在随访分析中，参与者被分为三组：HIIT 组（继续在家进行 LOW-HIIT）、EX 组（继续进行其他家庭锻炼）和 NO-EX 组（停止 LOW-HIIT/锻炼）。在 T-2 时，VO（增加 1.5 毫升/公斤/分钟， = 0.002）、平均动脉血压（MAB，下降 4 毫米汞柱， < 0.001）、HbA（下降 0.2%， = 0.005）和自我报告的生活质量（QoL，增加 5 分， < 0.001）得到改善。在 T-3 时，HIIT 组维持 VO 和 QoL，并进一步改善 MAB。EX 组维持 MAB 和 QoL，但 VO 下降。在 NON-EX 中，VO、MAB 和 QoL 恶化。我们得出结论，LOW-HIIT 可被视为改善现实生活条件中心血管代谢健康和减轻封锁期间与身体不活动相关的负面健康影响的有希望的选择。
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