Department of Human Studies, University of Alabama at Birmingham, Education Building, 205 901 13th St. South, Birmingham, AL, 35294, USA.
Department of Pediatrics, Birmingham, USA.
Trials. 2022 Aug 4;23(1):633. doi: 10.1186/s13063-022-06585-2.
The number of exercise trials examining cardiometabolic outcomes in spinal cord injury (SCI) is low, and prescribed exercise is often inconvenient for individuals with SCI to perform within their community. Individuals with SCI experience a myriad of barriers to exercise participation, which can include a lack of time, accessible or usable equipment and facilities, and transportation. Thus, it is imperative to identify effective modes of exercise that provide the greatest overall health benefits but do not require a significant time commitment. Low-volume high intensity interval training (HIIT) has demonstrated the same improvements in cardiometabolic health as moderate intensity exercise training (MIT), despite only requiring 20% of the total time commitment in adults without disabilities and more recently in individuals with SCI.
The primary purpose of this study is to integrate a 16 week home-based telehealth HIIT arm crank exercise training program in individuals with SCI and assess changes in cardiometabolic health.
Men and women between the ages of 19 and 60 with a confirmed diagnosis of SCI between C7 and T12 will be recruited for this study. Participants will be randomized to 16 weeks of telehealth HIIT exercise two days per week or a no-exercise control group. Aerobic capacity, muscular strength, blood lipids, glucose tolerance, resting energy expenditure, blood pressure, and body composition will be assessed at baseline and 16 weeks post-training.
Inactivity associated with SCI leads to chronic cardiometabolic health conditions. The majority of exercise interventions to date show that exercise is capable of increasing physical function, aerobic capacity, and muscle mass, and strength. Additionally, we have recently shown the ability of HIIT to improve blood lipid and glucose concentrations. Advances in telehealth exercise approaches have improved the capability to prescribe home-based exercise programs. Therefore, we hypothesize that the utilization of a home-based telehealth HIIT program will improve cardiometabolic health markers, yield high adherence (> 75%), and will be more enjoyable in individuals with SCI.
Telehealth High-Intensity Interval Exercise and Cardiometabolic Health in Spinal Cord Injury NCT04940598.
研究脊髓损伤(SCI)中心血管代谢结果的运动试验数量较少,而且规定的运动对于社区内的 SCI 患者来说往往不太方便进行。SCI 患者在参与运动时会遇到各种障碍,包括缺乏时间、可及或可用的设备和设施以及交通问题。因此,识别能够提供最大整体健康益处但不需要大量时间投入的有效运动模式至关重要。低容量高强度间歇训练(HIIT)已证明在心血管代谢健康方面与中等强度运动训练(MIT)同样有效,尽管在没有残疾的成年人中只需要总时间投入的 20%,最近在 SCI 患者中也证明了这一点。
本研究的主要目的是在 SCI 患者中整合 16 周基于家庭的远程健康 HIIT 扶手曲柄运动训练计划,并评估心血管代谢健康的变化。
将招募年龄在 19 至 60 岁之间、确诊为 C7 至 T12 之间 SCI 的男性和女性参加本研究。参与者将随机分为 16 周远程健康 HIIT 运动,每周两天,或不进行运动的对照组。在基线和 16 周培训后,将评估有氧能力、肌肉力量、血脂、葡萄糖耐量、静息能量消耗、血压和身体成分。
SCI 导致的不活动会导致慢性心血管代谢健康状况。迄今为止,大多数运动干预研究表明,运动能够提高身体机能、有氧能力和肌肉质量和力量。此外,我们最近还证明了 HIIT 改善血脂和血糖浓度的能力。远程健康运动方法的进步提高了制定家庭运动计划的能力。因此,我们假设利用基于家庭的远程健康 HIIT 计划将改善心血管代谢健康指标,获得高依从性(>75%),并且对 SCI 患者更具吸引力。
远程健康高强度间歇运动和脊髓损伤的心血管代谢健康 NCT04940598。