• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

死海地区银屑病的紫外线测量和光疗：25 年的经验。

Ultraviolet Measurements and Photoclimatotherapy for Psoriasis at the Dead Sea: 25 Years of Experience.

机构信息

Blaustein Institutes for Desert Research, ED Bergmann Campus, Ben-Gurion University of the Negev, Beer Sheva 8410506, Israel.

The Dead Sea and Arava Science Center, Masada 86910, Israel.

出版信息

Int J Environ Res Public Health. 2022 Sep 28;19(19):12364. doi: 10.3390/ijerph191912364.

DOI:10.3390/ijerph191912364
PMID:36231663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9566427/
Abstract

BACKGROUND

The Dead Sea basin is the lowest terrestrial site on the globe and is internationally recognized as a photoclimatotherapy center. Since the last century, questions were raised regarding a possible presence of unique incident ultraviolet irradiation, allowing the successful treatment of psoriasis, atopic dermatitis and other dermatological diseases.

AIM

This research study aims to determine the characteristics of solar ultraviolet irradiation and to understand the mechanism of action of photoclimatotherapy while applying results to clinical protocols of treatments.

METHODS

A meteorological station was established at the Dead Sea basin to continuously measure global, UVB and UVA irradiation. The same irradiation parameters are also monitored continuously by a set of identical ultraviolet irradiation instruments installed on the campus of the Ben-Gurion University of the Negev in Beer Sheva.

RESULTS

This study details the results of these long-term measurements, as well as their correlation with the success obtained by clinicians treating psoriasis patients.

CONCLUSIONS

A database of more than 25 years has enabled medical staff to establish tailor-made protocols for sun-exposure time intervals as a function of particular month and hour of day. The availability of such information significantly improved the results of photoclimatotherapy for psoriasis and simultaneously increased the safety of sun exposure at the Dead Sea.

摘要

背景

死海流域是地球上陆地海拔最低的地方，国际上公认其为光疗气候治疗中心。自上个世纪以来，人们就提出了一个问题，即在死海地区是否存在独特的、高剂量紫外线辐射，从而可以成功治疗银屑病、特应性皮炎和其他皮肤病。

目的

本研究旨在确定太阳紫外线辐射的特征，并了解光疗气候治疗的作用机制，同时将结果应用于临床治疗方案。

方法

在死海流域建立了一个气象站，以连续测量全球、UVB 和 UVA 辐射。在本古里安大学内的 Beer Sheva 分校的校园里，也安装了一套相同的紫外线辐射仪器，以连续监测相同的辐射参数。

结果

本研究详细介绍了这些长期测量的结果，以及它们与临床医生治疗银屑病患者的成功之间的相关性。

结论

超过 25 年的数据库使医务人员能够根据特定的月份和一天中的时间，制定出针对日光暴露时间间隔的个性化方案。这些信息的可用性显著提高了光疗气候治疗银屑病的效果，同时提高了在死海地区日光暴露的安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/75260d2545a6/ijerph-19-12364-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/c0acec85f800/ijerph-19-12364-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/ba365988e2d6/ijerph-19-12364-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/fd331698529a/ijerph-19-12364-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/de255393f6ac/ijerph-19-12364-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/cfa85e1d1f02/ijerph-19-12364-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/75260d2545a6/ijerph-19-12364-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/c0acec85f800/ijerph-19-12364-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/ba365988e2d6/ijerph-19-12364-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/fd331698529a/ijerph-19-12364-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/de255393f6ac/ijerph-19-12364-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/cfa85e1d1f02/ijerph-19-12364-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb1e/9566427/75260d2545a6/ijerph-19-12364-g006.jpg

相似文献

1
Ultraviolet Measurements and Photoclimatotherapy for Psoriasis at the Dead Sea: 25 Years of Experience.死海地区银屑病的紫外线测量和光疗：25 年的经验。
Int J Environ Res Public Health. 2022 Sep 28;19(19):12364. doi: 10.3390/ijerph191912364.
2
Ultraviolet radiation properties as applied to photoclimatherapy at the Dead Sea.应用于死海光气候疗法的紫外线辐射特性。
Int J Dermatol. 2003 May;42(5):359-65. doi: 10.1046/j.1365-4362.2003.01683.x.
3
Dead Sea ultraviolet climatotherapy for children with atopic dermatitis.死海紫外线气候疗法治疗特应性皮炎患儿
Photodermatol Photoimmunol Photomed. 2016 Sep;32(5-6):254-261. doi: 10.1111/phpp.12250. Epub 2016 Jul 26.
4
Intercomparison of global, ultraviolet B and A radiation measurements in the Dead Sea region (Ein Bokek) and Beer Sheva.死海地区（艾因布凯克）与贝尔谢巴全球、紫外线B及紫外线A辐射测量的比对
Isr J Med Sci. 1996 Jul;32 Suppl:S24-7.
5
Increased levels of enkephalin following natural sunlight (combined with salt water bathing at the Dead Sea) and ultraviolet A irradiation.自然阳光照射（结合在死海进行盐水浴）和紫外线A照射后脑啡肽水平升高。
Br J Dermatol. 1998 Dec;139(6):1012-9. doi: 10.1046/j.1365-2133.1998.02557.x.
6
The measurement and analysis of normal incidence solar UVB radiation and its application to the photoclimatherapy protocol for psoriasis at the Dead Sea, Israel.正常入射太阳 UVB 辐射的测量和分析及其在以色列死海银屑病光疗方案中的应用。
Photochem Photobiol. 2011 Jan-Feb;87(1):215-22. doi: 10.1111/j.1751-1097.2010.00842.x. Epub 2010 Nov 19.
7
Determination of solar ultraviolet dose in the Dead Sea treatment of psoriasis.死海治疗银屑病中太阳紫外线剂量的测定。
Isr Med Assoc J. 2003 Feb;5(2):87-8.
8
Indoor salt water baths followed by artificial ultraviolet B light for chronic plaque psoriasis.慢性斑块状银屑病采用室内盐水浴后辅以人工紫外线B照射治疗。
Cochrane Database Syst Rev. 2020 May 5;5(5):CD011941. doi: 10.1002/14651858.CD011941.pub2.
9
Advances in phototherapy for psoriasis and atopic dermatitis.光疗在银屑病和特应性皮炎中的进展。
Expert Rev Clin Immunol. 2019 Nov;15(11):1205-1214. doi: 10.1080/1744666X.2020.1672537. Epub 2019 Oct 1.
10
The impact of therapeutic modalities on patients with atopic dermatitis, psoriasis and vitiligo treated with phototherapy in the Jagiellonian University Outpatient Clinic.雅盖隆大学门诊诊所中，治疗方式对接受光疗的特应性皮炎、银屑病和白癜风患者的影响。
Pol Merkur Lekarski. 2019 Mar 28;46(273):125-129.

引用本文的文献

1
Secukinumab and Dead Sea Climatotherapy Impact Resolved Psoriasis Skin Differently Potentially Affecting Disease Memory.司库奇尤单抗和死海气候疗法对已治愈银屑病皮肤的影响不同，可能会影响疾病记忆。
Int J Mol Sci. 2024 May 31;25(11):6086. doi: 10.3390/ijms25116086.
2
Phytocannabinoids in the Pharmacotherapy of Psoriasis.植物大麻素在银屑病治疗中的应用。
Molecules. 2023 Jan 25;28(3):1192. doi: 10.3390/molecules28031192.

本文引用的文献

1
Mind-Body Interventions as Alternative and Complementary Therapies for Psoriasis: A Systematic Review of the English Literature.身心干预作为银屑病的替代和补充疗法：对英文文献的系统评价
Medicina (Kaunas). 2021 Apr 23;57(5):410. doi: 10.3390/medicina57050410.
2
Commentary: Effect of Dead Sea Climatotherapy on Psoriasis; A Prospective Cohort Study.评论：死海气候疗法对银屑病的影响；一项前瞻性队列研究。
Front Med (Lausanne). 2020 Nov 20;7:586418. doi: 10.3389/fmed.2020.586418. eCollection 2020.
3
Effect of Dead Sea Climatotherapy on Psoriasis; A Prospective Cohort Study.
死海气候疗法对银屑病的影响；一项前瞻性队列研究。
Front Med (Lausanne). 2020 Mar 18;7:83. doi: 10.3389/fmed.2020.00083. eCollection 2020.
4
Effect of the Dead Sea climatotherapy for psoriasis on quality of life.死海气候疗法对银屑病患者生活质量的影响。
Isr Med Assoc J. 2013 Feb;15(2):99-102.
5
The solar ultraviolet B radiation protection provided by shading devices with regard to its diffuse component.遮阳设备对太阳紫外线 B 辐射的漫射部分的防护作用。
Photodermatol Photoimmunol Photomed. 2011 Oct;27(5):236-44. doi: 10.1111/j.1600-0781.2011.00608.x.
6
The measurement and analysis of normal incidence solar UVB radiation and its application to the photoclimatherapy protocol for psoriasis at the Dead Sea, Israel.正常入射太阳 UVB 辐射的测量和分析及其在以色列死海银屑病光疗方案中的应用。
Photochem Photobiol. 2011 Jan-Feb;87(1):215-22. doi: 10.1111/j.1751-1097.2010.00842.x. Epub 2010 Nov 19.
7
Effectiveness of climatotherapy at the Dead Sea for psoriasis vulgaris: A community-oriented study introducing the 'Beer Sheva Psoriasis Severity Score'.死海气候疗法对寻常型银屑病的疗效：一项引入“贝尔谢巴银屑病严重程度评分”的社区导向性研究。
J Dermatolog Treat. 2005;16(5-6):308-13. doi: 10.1080/09546630500375841.
8
[Preliminary report; the therapeutic effect of the hot springs of Zohar (Dead Sea) on some skin diseases].[初步报告；佐哈尔（死海）温泉对某些皮肤病的治疗效果]
Harefuah. 1959 Sep 15;57:143-5.
9
Bioclimatology and balneology in dermatology: a Dead Sea perspective.皮肤科中的生物气候学与浴疗学：以死海为例
Clin Dermatol. 1998 Nov-Dec;16(6):695-8. doi: 10.1016/s0738-081x(98)00059-5.
10
Demographic evaluation of successful antipsoriatic climatotherapy at the Dead Sea (Israel) DMZ Clinic.以色列死海 DMZ 诊所成功的银屑病气候疗法的人口统计学评估。
Int J Dermatol. 1997 Apr;36(4):304-8. doi: 10.1046/j.1365-4362.1997.00204.x.