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经颅直流电刺激对健康老年人即时记忆、潜在学习和工作记忆的增强作用。

Enhancing Immediate Memory, Potential Learning, and Working Memory with Transcranial Direct Current Stimulation in Healthy Older Adults.

机构信息

Department of Developmental Psychology, Faculty of Psychology, University of Valencia, Av. Blasco Ibañez 21, 46010 Valencia, Spain.

Department of Methodology, Faculty of Psychology, University of Valencia, Av. Blasco Ibañez 21, 46010 Valencia, Spain.

出版信息

Int J Environ Res Public Health. 2022 Oct 5;19(19):12716. doi: 10.3390/ijerph191912716.

Abstract

BACKGROUND

Transcranial direct current stimulation (tDCS) has emerged as a prevention method or minimizer of the normal cognitive deterioration that occurs during the aging process. tDCS can be used to enhance cognitive functions such as immediate memory, learning, or working memory in healthy subjects. The objective of this study was to analyze the effect of two 20-min sessions of anodal transcranial direct stimulation on immediate memory, learning potential, and working memory in healthy older adults.

METHODS

A randomized, single-blind, repeated-measures, sham-controlled design was used. The sample is made up of 31 healthy older adults, of whom 16 were in the stimulation group and 15 were in the sham group. The anode was placed on position F7, coinciding with the left dorsolateral prefrontal cortex region, and the cathode was placed on Fp2, the right supraorbital area (rSO).

RESULTS

When comparing the results of the treatment group and the sham group, differences were observed in working memory and learning potential; however, no differences in immediate memory were found.

CONCLUSION

The results showed that tDCS is a non-invasive and safe tool to enhance cognitive processes in healthy older adults interested in maintaining some cognitive function.

摘要

背景

经颅直流电刺激(tDCS)已成为预防正常认知随衰老过程而下降的方法或最小化手段。tDCS 可用于增强健康受试者的即时记忆、学习或工作记忆等认知功能。本研究的目的是分析两次 20 分钟的阳极经颅直流电刺激对健康老年人即时记忆、学习潜能和工作记忆的影响。

方法

采用随机、单盲、重复测量、假刺激对照设计。样本由 31 名健康老年人组成,其中 16 名在刺激组,15 名在假刺激组。阳极放置在 F7 位置,与左背外侧前额叶区域重合,阴极放置在 Fp2 位置,右眶上区(rSO)。

结果

在比较治疗组和假刺激组的结果时,观察到工作记忆和学习潜能的差异;然而,即时记忆没有差异。

结论

结果表明,tDCS 是一种非侵入性和安全的工具,可增强对维持某些认知功能感兴趣的健康老年人的认知过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8688/9564946/c71e168611a7/ijerph-19-12716-g001.jpg

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