van den Heuvel M J, Dayan A D, Shillaker R O
Hum Toxicol. 1987 Jul;6(4):279-91. doi: 10.1177/096032718700600405.
This study has shown that the new approach to acute oral toxicity testing proposed by the British Toxicology Society: provides the information on the toxic effects of materials necessary for human risk assessment, can be used to rank materials for regulatory purposes on the basis of their acute toxicity, provides advantages for animal welfare by requiring the use of fewer animals than conventional acute oral toxicity tests and by subjecting those animals used to less chance of experiencing pain or distress.
本研究表明，英国毒理学学会提出的急性经口毒性测试新方法：能提供人类风险评估所需的材料毒性效应信息，可用于根据材料的急性毒性对其进行监管排序，相较于传统急性经口毒性测试，通过减少动物使用数量以及降低所用动物经历疼痛或痛苦的几率，为动物福利带来了益处。
