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基于卷积循环神经网络的 60GHz 频移连续波雷达的睡眠呼吸暂停低通气事件自动检测:一项前瞻性队列研究的初步报告。

Automated Detection of Sleep Apnea-Hypopnea Events Based on 60 GHz Frequency-Modulated Continuous-Wave Radar Using Convolutional Recurrent Neural Networks: A Preliminary Report of a Prospective Cohort Study.

机构信息

Department of Radiology, Armed Forces Yangju Hospital, Yangju 11429, Korea.

Department of Radiology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul 07061, Korea.

出版信息

Sensors (Basel). 2022 Sep 21;22(19):7177. doi: 10.3390/s22197177.

Abstract

Radar is a promising non-contact sensor for overnight polysomnography (PSG), the gold standard for diagnosing obstructive sleep apnea (OSA). This preliminary study aimed to demonstrate the feasibility of the automated detection of apnea-hypopnea events for OSA diagnosis based on 60 GHz frequency-modulated continuous-wave radar using convolutional recurrent neural networks. The dataset comprised 44 participants from an ongoing OSA cohort, recruited from July 2021 to April 2022, who underwent overnight PSG with a radar sensor. All PSG recordings, including sleep and wakefulness, were included in the dataset. Model development and evaluation were based on a five-fold cross-validation. The area under the receiver operating characteristic curve for the classification of 1-min segments ranged from 0.796 to 0.859. Depending on OSA severity, the sensitivities for apnea-hypopnea events were 49.0-67.6%, and the number of false-positive detections per participant was 23.4-52.8. The estimated apnea-hypopnea index showed strong correlations (Pearson correlation coefficient = 0.805-0.949) and good to excellent agreement (intraclass correlation coefficient = 0.776-0.929) with the ground truth. There was substantial agreement between the estimated and ground truth OSA severity (kappa statistics = 0.648-0.736). The results demonstrate the potential of radar as a standalone screening tool for OSA.

摘要

雷达是一种有前途的非接触式传感器,可用于整夜多导睡眠图(PSG),这是诊断阻塞性睡眠呼吸暂停(OSA)的金标准。这项初步研究旨在展示基于 60GHz 调频连续波雷达和卷积递归神经网络自动检测呼吸暂停低通气事件以进行 OSA 诊断的可行性。该数据集包含来自正在进行的 OSA 队列的 44 名参与者,他们于 2021 年 7 月至 2022 年 4 月期间使用雷达传感器接受了整夜 PSG。所有 PSG 记录,包括睡眠和清醒状态,都包含在数据集中。模型开发和评估基于五重交叉验证。用于分类 1 分钟片段的接收器工作特征曲线下面积的范围为 0.796 至 0.859。根据 OSA 严重程度,呼吸暂停低通气事件的灵敏度为 49.0-67.6%,每个参与者的假阳性检测次数为 23.4-52.8。估计的呼吸暂停低通气指数与真实值显示出强烈的相关性(皮尔逊相关系数=0.805-0.949)和良好到极好的一致性(组内相关系数=0.776-0.929)。估计的和真实的 OSA 严重程度之间存在实质性的一致性(kappa 统计量=0.648-0.736)。结果表明,雷达作为 OSA 的独立筛查工具具有潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d01/9570824/0b243defa456/sensors-22-07177-g001.jpg

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