使用深度学习对帕金森病患者的任务和震颤类型进行分类。

Using Deep Learning for Task and Tremor Type Classification in People with Parkinson's Disease.

机构信息

Department of Electrical and Computer Engineering, Western University, London, ON N6A 5B9, Canada.

School of Biomedical Engineering, Western University, London, ON N6A 5B9, Canada.

出版信息

Sensors (Basel). 2022 Sep 27;22(19):7322. doi: 10.3390/s22197322.

Abstract

Hand tremor is one of the dominating symptoms of Parkinson's disease (PD), which significantly limits activities of daily living. Along with medications, wearable devices have been proposed to suppress tremor. However, suppressing tremor without interfering with voluntary motion remains challenging and improvements are needed. The main goal of this work was to design algorithms for the automatic identification of the tremor type and voluntary motions, using only surface electromyography (sEMG) data. Towards this goal, a bidirectional long short-term memory (BiLSTM) algorithm was implemented that uses sEMG data to identify the motion and tremor type of people living with PD when performing a task. Moreover, in order to automate the training process, hyperparamter selection was performed using a regularized evolutionary algorithm. The results show that the accuracy of task classification among 15 people living with PD was 84±8%, and the accuracy of tremor classification was 88±5%. Both models performed significantly above chance levels (20% and 33% for task and tremor classification, respectively). Thus, it was concluded that the trained models, based on using purely sEMG signals, could successfully identify the task and tremor types.

摘要

手部震颤是帕金森病(PD)的主要症状之一,它严重限制了患者的日常生活活动。除了药物治疗外,还提出了可穿戴设备来抑制震颤。然而,在不干扰自主运动的情况下抑制震颤仍然具有挑战性,需要进行改进。这项工作的主要目标是设计仅使用表面肌电图(sEMG)数据自动识别震颤类型和自主运动的算法。为此,实现了一种双向长短期记忆(BiLSTM)算法,该算法使用 sEMG 数据来识别患有 PD 的人在执行任务时的运动和震颤类型。此外,为了实现训练过程的自动化,使用正则化进化算法进行了超参数选择。结果表明,在 15 名患有 PD 的人中,任务分类的准确率为 84±8%,震颤分类的准确率为 88±5%。两个模型的表现均显著优于随机水平(任务和震颤分类的准确率分别为 20%和 33%)。因此,可以得出结论,基于纯 sEMG 信号训练的模型可以成功识别任务和震颤类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d83/9570986/9eca958cedc1/sensors-22-07322-g001.jpg

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