IBM Research - Zurich, Switzerland.
Swiss Epilepsy Center, Zurich, Switzerland.
AMIA Annu Symp Proc. 2021 Jan 25;2020:1003-1011. eCollection 2020.
Continuous patient monitoring is essential to achieve an effective and optimal patient treatment in the intensive care unit. In the specific case of epilepsy it is the only way to achieve a correct diagnosis and a subsequent optimal medication plan if possible. In addition to automatic vital sign monitoring, epilepsy patients need manual monitoring by trained personnel, a task that is very difficult to be performed continuously for each patient. Moreover, epileptic manifestations are highly personalized even within the same type of epilepsy. In this work we assess two machine learning methods, dictionary learning and an autoencoder based on long short-term memory (LSTM) cells, on the task of personalized epileptic event detection in videos, with a set of features that were specifically developed with an emphasis on high motion sensitivity. According to the strengths of each method we have selected different types of epilepsy, one with convulsive behaviour and one with very subtle motion. The results on five clinical patients show a highly promising ability of both methods to detect the epileptic events as anomalies deviating from the stable/normal patient status.
在重症监护病房中,持续的患者监测对于实现有效的和最佳的患者治疗至关重要。在癫痫的具体情况下,这是唯一能够做出正确诊断并在可能的情况下制定后续最佳药物治疗方案的方法。除了自动生命体征监测外,癫痫患者还需要经过培训的人员进行手动监测,而对于每个患者来说,连续执行这项任务非常困难。此外,癫痫发作的表现即使在同一种癫痫类型中也具有高度的个体差异。在这项工作中,我们评估了两种机器学习方法,字典学习和基于长短期记忆(LSTM)细胞的自动编码器,用于在视频中进行个性化癫痫事件检测的任务,使用了一组特别开发的特征,重点是具有高运动敏感性。根据每种方法的优势,我们选择了两种不同类型的癫痫,一种具有惊厥行为,另一种则具有非常微妙的运动。对五名临床患者的结果表明,这两种方法都具有非常高的潜力,可以检测出异常的癫痫事件,这些事件偏离了稳定/正常的患者状态。