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在进行基础皮下注射疗程后,使用肠溶包衣变应原进行口服减敏作为延伸治疗。

Oral hyposensitisation with enteric-coated allergens as extension therapy following a basic subcutaneous course of injections.

作者信息

Horak F, Wheeler A W

出版信息

Int Arch Allergy Appl Immunol. 1987;84(1):74-8. doi: 10.1159/000234401.

DOI:10.1159/000234401
PMID:3623712
Abstract

We investigated in grass-pollen-sensitive adults the efficacy and safety of a therapeutic hyposensitisation regimen consisting of a basic pre-seasonal course of tyrosine-absorbed glutaraldehyde-modified grass pollen extract (Pollinex), followed by oral extension treatment using encapsulated, particulate, enteric-coated grass pollen allergen. The daily recorded symptom scores both of these patients and of others treated with complete basic and extension courses of Pollinex indicated that both sets of patients had fared better during the grass pollen season than control patients who had received only the basic Pollinex injections.

摘要

我们对草花粉敏感的成年人进行了研究,一种治疗性减敏方案包括一个基本的季节性前酪氨酸吸附戊二醛修饰草花粉提取物(Pollinex)疗程,随后采用封装的、颗粒状、肠溶包衣草花粉过敏原进行口服延长治疗。这些患者以及接受完整基本疗程和延长疗程Pollinex治疗的其他患者每日记录的症状评分表明,两组患者在草花粉季节的情况都比仅接受基本Pollinex注射的对照患者要好。

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Int Arch Allergy Appl Immunol. 1987;84(1):74-8. doi: 10.1159/000234401.
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引用本文的文献

1
Allergen immunotherapy.变应原免疫疗法
Curr Allergy Asthma Rep. 2001 Nov;1(6):491-7. doi: 10.1007/s11882-001-0057-8.
2
Seasonal allergic rhinitis. Newer treatment approaches.季节性变应性鼻炎。新的治疗方法。
Drugs. 1993 Apr;45(4):518-27. doi: 10.2165/00003495-199345040-00004.