Liu Wei, Jin Fan, Wang He-Mei, Yong Fang-Fang, Wu Zhen, Jia Hui-Qun
Department of Anesthesiology, The Forth hospital of Hebei Medical University, Shijiazhuang, China.
Department of Anesthesiology, Zhuji People's Hospital, Shaoxing, China.
Front Oncol. 2022 Sep 27;12:1011849. doi: 10.3389/fonc.2022.1011849. eCollection 2022.
Both double-lumen tube (DLT) and bronchial blocker (BB) are used for lung isolation in patients undergoing lung cancer surgery. However, the effects of different devices for lung isolation remain inconclusive. Present study was designed to investigate the association between the choice of the two devices and postoperative pulmonary complications (PPCs) in patients with lung cancer.
In this retrospective cohort study, patients who underwent lung cancer surgery between January 1, 2020 and October 31, 2020 were screened. Patients were divided into two groups according to different devices for lung isolation: DLT group and BB group. Primary outcome was the incidence of a composite of PPCs during postoperative in-hospital stay.
A total of 1721 were enrolled for analysis, of them, 868 received DLT and 853 BB. A composite of PPCs was less common in patients with BB (25.1%, [214/853]) than those received DLT (37.9% [329/868] OR 0.582 95% CI 0.461-0.735 P < 0.001). Respiratory infection was less common in BB group (14.4%, [123/853]) than DLT group (30.3%, [263/868], P<0.001). The incidence of non-PPCs complications was not statistically significant between the 2 groups.
For patients undergoing surgery for lung cancer, the use of BB for lung isolation was associated with a reduced risk of PPCs when compared with DLT.
双腔支气管导管（DLT）和支气管封堵器（BB）均用于肺癌手术患者的肺隔离。然而，不同肺隔离装置的效果仍无定论。本研究旨在探讨这两种装置的选择与肺癌患者术后肺部并发症（PPCs）之间的关联。
在这项回顾性队列研究中，筛选了2020年1月1日至2020年10月31日期间接受肺癌手术的患者。根据不同的肺隔离装置将患者分为两组：DLT组和BB组。主要结局是术后住院期间PPCs综合发生率。
共有1721例患者纳入分析，其中868例接受DLT，853例接受BB。BB组患者发生PPCs综合情况（25.1%，[214/853]）比接受DLT组（37.9%，[329/868]，OR 0.582，95%CI 0.461 - 0.735，P < 0.001）少见。BB组呼吸道感染发生率（14.4%，[123/853]）低于DLT组（30.3%，[263/868]，P < 0.001）。两组非PPCs并发症发生率无统计学差异。
对于接受肺癌手术的患者，与DLT相比，使用BB进行肺隔离与降低PPCs风险相关。
