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先天性心脏病手术后免疫功能正常患者的侵袭性肺曲霉病：一例报告

[Invasive Pulmonary Aspergillosis in a Immunocompetent Patient after Congenital Heart Disease Surgery: A Case Report].

作者信息

Ji So-Hyun, Yoo Seung-Jin, Park Eun-Ah, Song Seung-Geun

出版信息

Taehan Yongsang Uihakhoe Chi. 2020 Nov;81(6):1529-1536. doi: 10.3348/jksr.2020.0014. Epub 2020 Sep 1.

DOI:10.3348/jksr.2020.0014
PMID:36237705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9431841/
Abstract

Invasive pulmonary aspergillosis (IPA) has been known to occur in immunocompromised patients, but has been rarely reported in immunocompetent patients. In immunocompetent patients, pulmonary fungal infections are not initially considered. This results in diagnosis and treatment delays, as well as poor prognosis. We report a case and serial CT findings of IPA in an immunocompetent 29-year-old male after congenital heart disease surgery.

摘要

侵袭性肺曲霉病（IPA）已知会发生在免疫功能低下的患者中，但在免疫功能正常的患者中鲜有报道。在免疫功能正常的患者中，肺部真菌感染最初并未被考虑在内。这导致了诊断和治疗的延迟，以及预后不良。我们报告了一例29岁免疫功能正常男性在先天性心脏病手术后发生IPA的病例及系列CT检查结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af00/9431841/11df42981e38/jksr-81-1529-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af00/9431841/11df42981e38/jksr-81-1529-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af00/9431841/11df42981e38/jksr-81-1529-g001.jpg

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本文引用的文献

1
Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium.侵袭性真菌病的共识定义修订与更新：来自欧洲癌症研究与治疗组织和真菌病研究组教育与研究联合会。
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Aspergillosis in the 'nonimmunocompromised' host.
非免疫功能低下宿主中的曲霉菌病。
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4
Computed tomography findings in invasive pulmonary aspergillosis in non-neutropenic transplant recipients and neutropenic patients, and their prognostic value.非中性粒细胞减少症移植受者和中性粒细胞减少症患者侵袭性肺曲霉病的计算机断层扫描表现及其预后价值。
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Factors associated with overall and attributable mortality in invasive aspergillosis.侵袭性曲霉病中与总死亡率和归因死亡率相关的因素。
Clin Infect Dis. 2008 Nov 1;47(9):1176-84. doi: 10.1086/592255.
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Post-operative aspergillosis.术后曲霉病
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