Kim Min Ju, Kim Jung Im, Won Kyu Yeoun, Lee Han Na
Taehan Yongsang Uihakhoe Chi. 2021 Jul;82(4):994-999. doi: 10.3348/jksr.2020.0131. Epub 2021 Jul 2.
Late recurrence over 10 years after surgery and endobronchial metastasis are some of the specific biological behaviors of renal cell carcinoma (RCC). The current report describes a case of solitary endobronchial metastasis at a subsegmental bronchus that developed 20 years after curative nephrectomy for RCC. A 71-year-old male was admitted to our hospital for pneumonia. Chest radiography showed multifocal ill-defined nodular opacities in the right lower lung zone, suggesting pneumonia. Subsequent chest CT confirmed pneumonic infiltration in the right lung. However, a 4.3-cm, well-defined, elongated mass with a branching pattern was also identified in the right lower lobe, and a right nephrectomy scar was detected on the covered upper abdomen. The patient had undergone right nephrectomy 20 years ago due to clear cell RCC. After right lower lobectomy, the postoperative pathological diagnosis was endobronchial metastatic clear cell RCC. Endobronchial metastasis should be considered in a patient with a history of RCC who presents with a suspected endobronchial tumor, even decades after curative surgery.
手术后10年以上的晚期复发和支气管内转移是肾细胞癌(RCC)的一些特定生物学行为。本报告描述了1例在RCC根治性肾切除术后20年出现的段以下支气管孤立性支气管内转移病例。一名71岁男性因肺炎入院。胸部X线检查显示右下肺区有多发边界不清的结节状阴影,提示肺炎。随后的胸部CT证实右肺有肺炎浸润。然而,在右下叶还发现了一个4.3厘米、边界清晰、呈分支状的细长肿块,在上腹部可见右肾切除瘢痕。该患者20年前因透明细胞RCC接受了右肾切除术。右下叶切除术后,术后病理诊断为支气管内转移性透明细胞RCC。对于有RCC病史且出现疑似支气管内肿瘤的患者,即使在根治性手术后数十年,也应考虑支气管内转移。