Debiche Soumaya, Snene Houda, Bouchabou Bochra, Attia Monia, Blibech Hana, Ayadi Aïda, Enneifer Rym, Ben Farhat Leila, Mehiri Nadia, Louzir Bechir
University of Tunis El Manar, Faculty of Medicine of Tunis, Mongi Slim La Marsa University Hospital, Department of Pulmonology and Allergology, Tunis, Tunisia.
University of Tunis El Manar, Faculty of Medicine of Tunis, Mongi Slim La Marsa University Hospital, Department of Gastroenterology, Tunis, Tunisia.
Tunis Med. 2024 Dec 5;102(12):1089-1095. doi: 10.62438/tunismed.v102i12.5202.
Endobronchial metastases (EBMs) are rare, with primary tumours predominantly of breast, renal, and colorectal origin. Bronchoscopy is the diagnostic gold standard, with histological confirmation through immunohistochemical study.
We presented three cases of EBMs, one secondary to colorectal cancer and two associated with renal tumours. EBM unveiled the extra-thoracic neoplasm in colorectal cancer and was incidentally discovered during renal cancer follow-up. Bronchoscopy revealed an obstructive endobronchial mass in two cases. Histological diagnosis was established via bronchial biopsies (collecting duct renal carcinoma), computed tomography-guided transparietal lung biopsy (clear cell renal carcinoma), and endobronchial mass resection through rigid bronchoscopy (colorectal adenocarcinoma).
In case of an endobronchial lesion, the diagnosis of EBM should be evoked especially when the medical history reports extra-thoracic neoplasms. This diagnostic hypothesis guides the histological diagnosis and leads to an appropriate treatment.
支气管内转移瘤（EBMs）较为罕见，原发肿瘤主要起源于乳腺、肾脏和结肠直肠。支气管镜检查是诊断的金标准，需通过免疫组织化学研究进行组织学确诊。
我们报告了3例支气管内转移瘤病例，1例继发于结肠直肠癌，2例与肾肿瘤相关。支气管内转移瘤在结肠直肠癌中揭示了胸外肿瘤，且在肾癌随访期间偶然发现。支气管镜检查在2例中发现了阻塞性支气管内肿物。通过支气管活检（集合管肾癌）、计算机断层扫描引导下经胸壁肺活检（透明细胞肾癌）以及通过硬支气管镜进行支气管内肿物切除（结肠直肠腺癌）确立了组织学诊断。
对于支气管内病变，尤其是当病史报告有胸外肿瘤时，应考虑支气管内转移瘤的诊断。这一诊断假设指导组织学诊断并导致适当的治疗。
