Two new triterpenoid glycosides from and their cytotoxic activity.

Using combined chromatographic methods, two new triterpenoid glycosides, bacopasaponin K () and bacopasaponin L (, along with eight known compounds, bacopaside IV (), bacopaside VII (), bacopasaponin E (), bacoside A (), bacopasaponin F (), bacopasaponin C (), bacopaside I (), and bacopaside II () were isolated from the methanol extract of the . Their structures were elucidated by 1D-, 2D-NMR spectroscopic analysis, HR-ESI-MS and comparing with the NMR data reported in the literature. All these compounds were evaluated for their cytotoxic activity using the cell counting kit-8 (CCK-8) assay. Compounds , , , and exhibited potential cytotoxic effects against human lung cancer cells (PC9) and human colon cancer cells (SW620).