Lifespan and Population Health, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Centre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester, United Kingdom.
PLoS One. 2022 Oct 14;17(10):e0275633. doi: 10.1371/journal.pone.0275633. eCollection 2022.
Medication errors are an important cause of morbidity and mortality. The pharmacist-led IT-based intervention to reduce clinically important medication errors (PINCER) intervention was shown to reduce medication errors when tested in a cluster randomised controlled trial and when implemented across one region of England. Now that it has been rolled out nationally, and to enhance findings from evaluations with staff and stakeholders, this paper is the first to report patients' perceived acceptability on the use of PINCER in primary care and proposes suggestions on how delivery of PINCER related care could be delivered in a way that is acceptable and not unnecessarily burdensome.
A total of 46 participants living with long-term health conditions who had experience of medication reviews and/or monitoring were recruited through patient participant groups and social media. Semi-structured, qualitative interviews and focus groups were conducted face-to-face or via telephone. A thematic analysis was conducted and findings mapped to the constructs of the Theoretical Framework of Acceptability (TFA).
Two themes were identified and interpreted within the most relevant TFA construct: Perceptions on the purpose and components of PINCER (Affective Attitude and Intervention Coherence) and Perceived patient implications (Burden and Self-efficacy). Overall perceptions on PINCER were positive with participants showing good understanding of the components. Access to medication reviews, which PINCER related care can involve, was reported to be limited and a lack of consistency in practitioners delivering reviews was considered challenging, as was lack of communication between primary care and other health-care providers. Patients thought it would be helpful if medication reviews and prescription renewal times were synchronised. Remote medication review consultations were more convenient for some but viewed as a barrier to communication by others. It was acknowledged that some patients may be more resistant to change and more willing to accept changes initiated by general practitioners.
Participants found the concept of PINCER acceptable; however, acceptability could be improved if awareness on the role of primary care pharmacists is raised and patient-pharmacist relationships enhanced. Being transparent with communication and delivering streamlined and consistent but flexible PINCER related care is recommended.
用药错误是发病率和死亡率的一个重要原因。基于 IT 的药师主导干预措施(PINCER)可减少临床重要的用药错误,这一干预措施在一项集群随机对照试验中得到了验证,并在英格兰的一个地区得到了实施。现在它已经在全国范围内推广,为了从员工和利益相关者的评估中增强发现,本文首次报告了患者对初级保健中使用 PINCER 的可接受性,并就如何以可接受且不会不必要地增加负担的方式提供与 PINCER 相关的护理提出了建议。
通过患者参与团体和社交媒体招募了 46 名患有长期健康状况的参与者,他们有药物审查和/或监测的经验。通过面对面或电话进行了半结构化的定性访谈和焦点小组讨论。对主题进行了分析,并将研究结果映射到可接受性理论框架(TFA)的构建中。
在最相关的 TFA 结构中确定并解释了两个主题:对 PINCER 的目的和组成部分的看法(情感态度和干预一致性)和对患者影响的看法(负担和自我效能)。总体而言,参与者对 PINCER 的看法是积极的,他们对组成部分有很好的理解。参与 PINCER 相关护理的药物审查的机会有限,且执业者提供审查的一致性被认为具有挑战性,因为初级保健和其他卫生保健提供者之间缺乏沟通。患者认为,如果能同步药物审查和处方更新时间,将会有所帮助。远程药物审查咨询对一些人来说更方便,但对其他人来说则认为这是沟通的障碍。人们认识到,一些患者可能更抵制变化,更愿意接受全科医生发起的变化。
参与者认为 PINCER 的概念是可以接受的;但是,如果提高对初级保健药剂师作用的认识并加强患者与药剂师的关系,可接受性可以进一步提高。建议保持沟通的透明度,并提供精简、一致但灵活的 PINCER 相关护理。